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Displaying results 3491 - 3500 of 10000 in total
  1. Drug

    Demeclocycline

    go.drugbank.com/drugs/DB00618
    Approved

    A tetracycline analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than tetracycline, it maintains effective blood levels for longer periods of time.

  2. Target

    Tumor necrosis factor receptor superfamily member 10B

    go.drugbank.com/bio_entities/BE0003433
    TargetHumans

    The adapter molecule FADD recruits caspase-8 to the activated receptor.

    Polypeptides: Tumor necrosis factor receptor superfamily member 10B
  3. Target

    Tumor necrosis factor receptor superfamily member 10A

    go.drugbank.com/bio_entities/BE0010564
    TargetHumans

    The adapter molecule FADD recruits caspase-8 to the activated receptor.

    Polypeptides: Tumor necrosis factor receptor superfamily member 10A
  4. Drug

    Bexotegrast

    go.drugbank.com/drugs/DB16515
    Investigational

    The compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in Series C financing to support further clinical … Phase 2a studies are currently evaluating PLN-74809 safety and efficacy for participants with IPF (NCT04396756)across 10 participating countries[L31703], and for participants with PSC (NCT04480840).

  5. Drug

    Technetium Tc-99m oxidronate

    go.drugbank.com/drugs/DB09139
    ApprovedWithdrawn

    [L1138] These complexes are formed by the binding of 99mTc to metal atoms of an organic molecule. … The group oxidronate falls into the category of diphosphonates whose structure allows them to bind to calcium.

    Synonyms: Technetium Tc 99m oxidronate, Technetium Tc-99m oxidronate
  6. Drug

    3-Fluoro-L-tyrosine

    go.drugbank.com/drugs/DB04436
    Experimental

    These are compounds whose structure contain a benzene ring conjugated to a propanoic acid. 3-Fluoro-L-tyrosine targets the protein superoxide dismutase [mn], mitochondrial. … This compound belongs to the phenylpropanoic acids.

    Synonyms: L-m-Fluorotyrosine
  7. Drug

    Icodextrin

    go.drugbank.com/drugs/DB00702
    ApprovedInvestigational

    Icodextrin is an iso-osmotic peritoneal dialysis solution containing glucose polymers. It is used primarily for ambulatory peritoneal dialysis (CAPD) of diabetic patients and automated peritoneal dialysis (APD) for patients with end-stag...

    Mixtures: EXTRANEFROL PERİTON DİYALİZ ÇÖZELTİSİ, 2000 ML TEKLİ, EXTRANEFROL PERİTON DİYALİZ ÇÖZELTİSİ, 2500 ML ÇİFTLİ
  8. Drug

    Estetrol

    go.drugbank.com/drugs/DB12235
    ApprovedInvestigational

    Estetrol is the first new estrogen introduced to the USA in over 50 years and is the first approved estetrol product in the world. … [L33184] Estetrol (E4) is a native estrogen occurring naturally during pregnancy, but can be synthesized from a plant source and used for contraception.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  9. Drug

    Temelimab

    go.drugbank.com/drugs/DB15634
    Investigational

    Temelimab is under investigation in clinical trial NCT02782858 (Clinical Trial Assessing the HERV-W Env Antagonist Gnbac1 for Efficacy in MS).

  10. Drug

    AMG-208

    go.drugbank.com/drugs/DB08079
    Investigational

    AMG-208 has been used in trials studying the treatment of Cancer, Tumors, Oncology, Prostate Cancer, and Oncology Patients, among others.