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Recombinant human plasma gelsolin
go.drugbank.com/drugs/DB15746InvestigationalPlasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.
Betazole
go.drugbank.com/drugs/DB00272ApprovedA histamine H2 agonist used clinically to test gastric secretory function.
Josamycin
go.drugbank.com/drugs/DB01321InvestigationalThe drug has antimicrobial activity against a wide spectrum of pathogens.
LI-301
go.drugbank.com/drugs/DB05509ExperimentalIt has a novel mode of action combining both the light effect of a Selective Serotonin Reuptake Inhibitor ("SSRI")(most likely antagonistic at 5HT1a receptors) and antagonism at mu-opioid receptors.
Androstenedione
go.drugbank.com/drugs/DB01536IllicitInvestigationalDepending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol.
Viral Macrophage-Inflammatory Protein
go.drugbank.com/drugs/DB15748ExperimentalViral macrophage inflammatory protein-II (vMIP) is a highly basic protein and human chemokine analog encoded by human herpesvirus-8. The structure of vMIP consists of 71 residues and is a monomer under most conditions. It helps its virus...
AT9283
go.drugbank.com/drugs/DB05169InvestigationalIt was discovered and developed internally using Astex’s fragment-based drug discovery platform, Pyramid.
Ligelizumab
go.drugbank.com/drugs/DB11856InvestigationalSimilar in mechanism to [omalizumab], another IgE-directed monoclonal antibody, ligelizumab has a distinct binding epitope as compared to its peer (with a small degree of overlap) which appears to confer … autoantibodies against IgE receptors, and sometimes against IgE itself, are thought to exist in 30-40% of patients,[A242362,A242367] and the efficacy anti-IgE antibody therapy in the treatment of CSU has
Creatine
go.drugbank.com/drugs/DB00148ApprovedInvestigationalNutraceuticalIn muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine.
Clocapramine
go.drugbank.com/drugs/DB09003ExperimentalClocapramine has been implicated in at least one strange death, including a suicide. … In addition to psychosis, clocapramine has also been used to augment antidepressants in the treatment of anxiety and panic.