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Paramethasone
go.drugbank.com/drugs/DB01384ExperimentalIt has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less
Categories: Sex Hormones and Insulins, Corticosteroids for Systemic UseDapsone
go.drugbank.com/drugs/DB00250ApprovedInvestigationalIt is also used with pyrimethamine in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) … Its mechanism of action is probably similar to that of the sulfonamides which involves inhibition of folic acid synthesis in susceptible organisms.
Categories: Antiinfectives for Systemic Use, Anti-Acne Preparations for Topical UseTebentafusp
go.drugbank.com/drugs/DB15283ApprovedInvestigationalTebentafusp is a gp100 peptide-HLA-directed CD3 T cell engager. … [A244815,A244910] Uveal melanoma is a rare ocular tumour with often poor prognosis and limited treatment options.
Tisotumab vedotin
go.drugbank.com/drugs/DB16732ApprovedInvestigationalIt is also being investigated for the combination use with other chemotherapeutic agents for recurrent or metastatic cervical cancer.[A238924] … TF is a novel target for cancers, as it is often overexpressed on solid tumours, including cervical cancer, and it is associated with poor clinical outcomes.
Thyroid, porcine
go.drugbank.com/drugs/DB09100ApprovedInvestigational[A190831,L11755] Thyroid extract has been described in literature to treat hypothyroidism since 1891[A190807] but its use dates back as far as the 6th century. … [A190813] Thyroid extracts were never FDA approved as their use in the United States predates the FDA.[A190831]
Synonyms: Sus scrofa thyroidStanolone
go.drugbank.com/drugs/DB02901IllicitInvestigationalDihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemFlotufolastat F-18
go.drugbank.com/drugs/DB17851ApprovedInvestigationalFlotufolastat F-18 is a diastereoisomer of <sup>18</sup>F-rhPSMA-7, and compared to the other diastereoisomers of this compound, flotufolastat F-18 has a faster clearance from blood pool, liver, and kidney … [A259846,L46731] In patients with recurrent prostate cancer that require localized treatment, the use of <sup>18</sup>F-labeled ligands for positron emission tomography (PET) offers accurate diagnostic
Telotristat ethyl
go.drugbank.com/drugs/DB12095Approved[A252937] Serotonin is metabolized in the urinary metabolite 5-hydroxy indole acetic acid (u5-HIAA), and high levels of u5-HIAA is associated with poor survival outcome in patients with NET. … Telotristat ethyl is a prodrug of telotristat that was approved by the FDA in March 2017 as Xermelo.
Valine
go.drugbank.com/drugs/DB00161ApprovedInvestigationalNutraceuticalValine is a branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Mixtures: AMINOACIDI S BIOINDUSTRIA L.I.M.Synonyms: (S)-Valine, (2S)-2-Amino-3-methylbutanoic acidVenetoclax
go.drugbank.com/drugs/DB11581ApprovedInvestigationalVenetoclax is used to treat chronic lymphocytic leukemia (CLL) and certain types of small lymphocytic lymphoma [FDA label]. CLL is the most prevalent leukemia diagnosed in Western countries [A40022]. … Venetoclax is a BCL-2 inhibitor that was initially approved by the FDA in April 2016 [FDA label].