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Favipiravir
go.drugbank.com/drugs/DB12466ApprovedInvestigationalDiscovered by Toyama Chemical Co., Ltd. in Japan, favipiravir is a modified pyrazine analog that was initially approved for therapeutic use in resistant cases of influenza. … [A191688,A191772,A191775] Not only does favipiravir inhibit replication of influenza A and B, but the drug has shown promise in the treatment of avian influenza, and may be an alternative option for
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2C8 InhibitorsProducts: L-VIRTasimelteon
go.drugbank.com/drugs/DB09071ApprovedInvestigationalIn blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. … Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamideBeractant
go.drugbank.com/drugs/DB06761ApprovedBeractant is a pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants. … It is suspended in 0.9% sodium chloride solution, and heat-sterilized.
Products: SURVANTA ® 4 ML, SURVANTA INTRATRAKEAL SUSPANSIYON, 1 ADETRisdiplam
go.drugbank.com/drugs/DB15305ApprovedInvestigational[L15351,A216871] Risdiplam was approved by the FDA in August 2020 for the treatment of spinal muscular atrophy (SMA). … Risdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA).
Categories: MATE 1 Inhibitors, MATE 2 InhibitorsLevobunolol
go.drugbank.com/drugs/DB01210ApprovedA nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: (S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenoneHexafluronium
go.drugbank.com/drugs/DB00941ApprovedHexafluronium bromide is a neuromuscular blocking agent used in anesthesiology to prolong and potentiate the skeletal muscle relaxing action of suxamethonium during surgery. … It is known to bind and block the activity of plasma cholinesterases.
Synonyms: Hexafluorenium ion, Hexamethylenebis(fluoren-9-yldimethylammonium)Fluorometholone
go.drugbank.com/drugs/DB00324ApprovedInvestigationalA glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
Mixtures: FLUFORTE-N-LIQUIFILM, FLU-SURE T® SUSPENSIÓN OFTÁLMICACategories: Corticosteroids, Moderately Potent (Group II), Cytochrome P-450 SubstratesPerflubron
go.drugbank.com/drugs/DB05791InvestigationalPerflubron (Oxygent) is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients.
Categories: Compounds used in a research, industrial, or household settingFructose
go.drugbank.com/drugs/DB04173ApprovedInvestigationalMixtures: Formula EmCategories: Compounds used in a research, industrial, or household settingTranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalIt also is useful in panic and phobic disorders (From AMA Drug Evaluations Annual, 1994, p311). … Tranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring.
Synonyms: (1R*,2S*)-2-phenylcyclopropan-1-amine, (±)-trans-2-phenylcyclopropylamineCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP1A2 Inhibitors