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Aluminum chloride
go.drugbank.com/drugs/DB11081ApprovedInvestigationalIn antiperspirant products, FDA approves the use of aluminum chloride as an active ingredient up to 15%, calculated on the hexahydrate form, in an aqueous solution nonaerosol dosage form [L2012]. … Aluminum chloride is a chemical compound with the chemical formula AlCl3. When contaminated with iron chloride, it often displays a yellow color compared to the white pure compound.
Categories: Compounds used in a research, industrial, or household settingProducts: Gingi Aid 10%, Ms HemostaticCocaine
go.drugbank.com/drugs/DB00907ApprovedIllicitInvestigationalIt also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat.
Synonyms: methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl esterCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNaltrexone
go.drugbank.com/drugs/DB00704ApprovedInvestigationalVet approvedIt is a narcotic antagonist that is effective orally, longer lasting and more potent than naloxone, and has been proposed for the treatment of heroin addiction. … Derivative of noroxymorphone that is the N-cyclopropylmethyl congener of naloxone.
Synonyms: N-Cyclopropylmethyl-14-hydroxydihydromorphinone, 17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-oneMixtures: Troxyca ER, Troxyca ERPyrazinamide
go.drugbank.com/drugs/DB00339ApprovedInvestigationalA pyrazine that is used therapeutically as an antitubercular agent.
Mixtures: RIFAMPICIN 75 MG/ISONIAZID 50 MG/PYRAZINAMIDE 150 MG, RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MGCategories: Heterocyclic Compounds, 1-RingAlpelisib
go.drugbank.com/drugs/DB12015ApprovedInvestigationalAlpelisib was designed to target this enzyme that appears to be mutated at a rate of nearly 30% in human cancers, leading to hyperactivation. … It works by selectively inhibiting class I PI3K p110α [A179203], which is the catalytic subunit of PI3K, a lipid kinase that plays a role in various biological processes, including proliferation, survival
Categories: Heterocyclic Compounds, 1-Ring, Class I Phosphatidylinositol 3-Kinases, antagonists & inhibitorsProducts: PİMREVA 200 MG FİLM KAPLI TABLET, 14 ADET, PİMREVA 200 MG FİLM KAPLI TABLET, 28 ADETSebelipase alfa
go.drugbank.com/drugs/DB11563ApprovedInvestigationalIt was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion Pharmaceuticals).[L39337,L39342] … [L39337] Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency.
Synonyms: SBC-102Products: KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION.Framycetin
go.drugbank.com/drugs/DB00452ApprovedInvestigationalA component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)
Synonyms: Neomycin B, Fradiomycin BInternational brands: Leukase NClevidipine
go.drugbank.com/drugs/DB04920ApprovedInvestigationalClevidipine is a dihydropyridine L-type calcium channel blocker that is selective for vascular smooth muscle and is indicated for blood pressure reduction when oral therapy is not an option.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: Cleviprex 0,5 mg/ml Emulsion zur InjektionTinzaparin
go.drugbank.com/drugs/DB06822ApprovedInvestigationalIt is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. … LMWHs are less effective at inactivating factor IIa due to their shorter length compared to unfractionated heparin.
Products: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INJECTION 14, 000 Anti-Xa IU/0.7mlBexarotene
go.drugbank.com/drugs/DB00307ApprovedInvestigationalBexarotene (Targretin) is an antineoplastic agent indicated by the FDA for Cutaneous T cell lymphoma. It has been used off-label for lung cancer, breast cancer, and Kaposi's sarcoma.
Synonyms: 4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid, p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acidCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers