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Displaying results 3541 - 3550 of 10000 in total
  1. Drug

    Tebipenem pivoxil

    go.drugbank.com/drugs/DB16840
    Approved

    [L57980] Tebipenem pivoxil is the first oral carbapenem approved in the United States, creating an outpatient option for patients who have limited or no alternative oral therapy. … [L57979] The FDA approved tebipenem pivoxil on June 17, 2026, for complicated urinary tract infections including pyelonephritis caused by designated susceptible organisms in adult patients who have

  2. Drug

    Droloxifene

    go.drugbank.com/drugs/DB15641
    Experimental

    It may have a particular role in situations in which rapid pharmacokinetics, or an increased antiestrogenic to estrogenic ratio, are required. … give it theoretical advantages over tamoxifen in the treatment of human breast cancer.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Amylocaine

    go.drugbank.com/drugs/DB09088
    ApprovedWithdrawn

    Elsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French word 'fourneau' as 'stove' in English [L1882]. … , and prilocaine in the 1940s and 1950s superseded and made the use of amylocaine obsolete.

  4. Drug

    Hydroxytyrosol

    go.drugbank.com/drugs/DB12771
    Investigational

    Hydroxytyrosol has been used in trials studying the prevention of Breast Cancer.

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Ellagic acid

    go.drugbank.com/drugs/DB08846
    Investigational

    In pomegranates, there are several therapeutic compounds but ellagic acid is the most active and abundant. Ellagic acid is also present in vegetables. … Ellagic acid is present in several fruits such as cranberries, strawberries, raspberries, and pomegranates.

  6. Drug

    Zidebactam

    go.drugbank.com/drugs/DB13090
    Approved

    [L63350] It is available only in fixed combination with [cefepime], which binds PBP3 and PBP1a/b. … Zidebactam is a diazabicyclooctane that acts both as a beta-lactamase inhibitor and as an antibacterial in its own right, selectively binding penicillin-binding protein 2.

  7. Drug

    Primaquine

    go.drugbank.com/drugs/DB01087
    ApprovedInvestigational

    It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. … An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide.

  8. Drug

    Aleglitazar

    go.drugbank.com/drugs/DB08915
    Investigational

    In the phase II clinical trial called SYNCHRONY, with type II diabetic patients, aleglitazar was able to control both lipid and glucose levels in a synergistic manner while also having limited side effects … Aleglitazar is an investigational drug from the company Hoffmann–La Roche and is currently in a phase III clinical trial called ALECARDIO.

  9. Drug

    AG-858

    go.drugbank.com/drugs/DB05502
    Investigational

    Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models. … AG-858 (autologous heat-shock protein 70 peptide vaccine) is a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes.

  10. Drug

    Eldecalcitol

    go.drugbank.com/drugs/DB05295
    Investigational

    Eldecalcitol (ED-71), a vitamin D analog, is a more potent inhibitor of bone resorption than alfacalcidol in an estrogen-deficient rat model of osteoporosis. … Eldecalcitol, effectively and safely increased lumbar and hip bone mineral density (BMD) in osteoporotic patients who also received vitamin D3 supplementation.