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Displaying results 3551 - 3560 of 10000 in total
  1. Drug

    Patritumab deruxtecan

    go.drugbank.com/drugs/DB21996
    Investigational

    Patritumab deruxtecan is under investigation in clinical trial NCT06596694 (Study of Patritumab Deruxtecan in Participants With Gastrointestinal Cancers (MK-1022-011) (HERTHENA-PanTumor02)).

  2. Drug

    Bremelanotide

    go.drugbank.com/drugs/DB11653
    Approved

    [A179686] The mechanism by which bremelanotide's action on receptors translates to a clinical effect is still unknown. … [A179683] Since then it was investigated for its place in treating sexual dysfunction in men and women but is now only indicated for women.

  3. Drug

    Peginesatide

    go.drugbank.com/drugs/DB08894
    ApprovedWithdrawn

    Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself. … Peginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine. FDA approved March 27, 2012.

  4. Indication

    Sickle Cell Disease

    go.drugbank.com/conditions/DBCOND0029334
    Drugs: Exagamglogene autotemcel · Lovotibeglogene autotemcel · Piracetam · Voxelotor
    Synonyms: Sickling Disorder Due to Hemoglobin S, Sickling disorder due to hemoglobin S (disorder)
  5. Drug

    Poliovirus type 2 antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB10796
    ApprovedInvestigational

    Poliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis caused by

    Mixtures: PENTAXİM 0,5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇİN TOZ İÇEREN FLAKON VE SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, Td Polio Adsorbed
  6. Target

    Beta-lactamase OXA-10

    go.drugbank.com/bio_entities/BE0001274
    TargetEnzymePseudomonas aeruginosa

    Hydrolyzes both carbenicillin and oxacillin.

    Polypeptides: Beta-lactamase OXA-10
  7. Drug

    V1003

    go.drugbank.com/drugs/DB05046
    Experimental

    Buprenorphine is a well-known analgesic and the intranasal formulation has the potential to provide a convenient alternative to other treatments, allowing patients to manage their post-operative pain both … prior to discharge from hospital and at home during their recovery period.

  8. Drug

    CIGB-258 peptide

    go.drugbank.com/drugs/DB15809
    Experimental

    CIGB-258 is a peptide that is immunoregulatory and derived from heat shock protein 60 of the cellular variant. … As of 2020, The Center for Genetic Engineering and Biotechnology (CIGB) in Havana, Cuba, is testing the treatment efficacy of this peptide in patients with COVID-19 who are under intensive therapy regimens

  9. Target

    Cytosolic 10-formyltetrahydrofolate dehydrogenase

    go.drugbank.com/bio_entities/BE0000933
    TargetHumans

    Cytosolic 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide (PubMed:19933275, PubMed:21238436).

    Polypeptides: Cytosolic 10-formyltetrahydrofolate dehydrogenaseSynonyms: 10-FTHFDH
  10. Target

    Bone morphogenetic protein 10

    go.drugbank.com/bio_entities/BE0010910
    TargetHumans

    Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.

    Polypeptides: Bone morphogenetic protein 10Synonyms: BMP-10