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Bisegliptin
go.drugbank.com/drugs/DB06127InvestigationalBisegliptin is a compound for the treatment of type 2 diabetes. … It is an orally active, dipeptidyl peptidase-IV (DPPIV) inhibitor which lowers blood glucose levels by blocking the degradation of the hormone GLP-1 thereby stimulating glucose-dependent insulin secretion
Categories: DPP-IV InhibitorsGemeprost
go.drugbank.com/drugs/DB08964ApprovedWithdrawnIt is not FDA-approved but available in Japan marketed as Preglandin. … Gemeprost is a prostaglandin E1 (PGE1) analog and antiprogestogen used for preoperative dilation of the cervix before surgical abortion.
Crovalimab
go.drugbank.com/drugs/DB16128ApprovedInvestigational[A263958] It soon gained its approval in Japan in the next month,[A263958] and in the USA in June of the same year. … Crovalimab is a humanized monoclonal antibody and complement C5 inhibitor.[L50908] It consists of two heavy chains (451 amino acid residues each) and two light chains (217 amino acid residues each).
Felodipine
go.drugbank.com/drugs/DB01023ApprovedIt acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity.
Products: FELODIPIN 2.5MG RET HEU N, FELODIPIN 1A PHARMA 5MGThiohexam
go.drugbank.com/drugs/DB14200ApprovedThiohexam is a rubber cure accelerator. It is also a known allergen and dermatological sensitizer. Sensitivity to Thiohexam may be identified with a clinical patch test.
Synonyms: N-cyclohexyl-2-Benzothiazosulfenamide, N-Cyclohexylbenzothiazol-2-sulfenamidCipepofol
go.drugbank.com/drugs/DB16295ApprovedInvestigational[L63809] The drug has a longer regulatory history outside the United States: China's National Medical Products Administration approved it in December 2020 under the trade name Sishuning, and its Chinese … [L63931] Cipepofol is approved in the United States for induction of general anesthesia in adults undergoing surgery, an approval Haisco announced on June 1, 2026.
Amoxapine
go.drugbank.com/drugs/DB00543ApprovedAmoxapine, the <i>N</i>-demethylated derivative of the antipsychotic agent loxapine, is a dibenzoxazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. … In depressed individuals, amoxapine exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake.
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic IndexPrenylamine
go.drugbank.com/drugs/DB04825ApprovedWithdrawnPrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Categories: Vasodilators Used in Cardiac DiseasesSynonyms: DL-prenylamine, N-(3,3-Diphenylpropyl)-alpha-methylphenaethylaminHydroxyamphetamine
go.drugbank.com/drugs/DB09352Approvedstinging in the eyes. … Hydroxyamphetamine is a derivative of amphetamines. Hydroxyamphetamine is intended mainly as local eye drops for diagnostic purposes.
Synonyms: dl-4-hydroxyamphetamine, dl-p-hydroxyamphetamine