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Displaying results 3561 - 3570 of 10000 in total
  1. Drug

    Reboxetine

    go.drugbank.com/drugs/DB00234
    ApprovedInvestigationalWithdrawn

    Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: EDRONAX 4 MG TABLET, 60 ADET, Edronax 4 mg - Tabletten
  2. Drug

    Dabocemagene autoficel

    go.drugbank.com/drugs/DB17878
    Investigational

    It comprises autologous dermal fibroblasts genetically modified to express functional type VII collagen.

    Synonyms: AUTOLOGOUS HUMAN DERMAL FIBROBLAST CELLS DERIVED FROM SKIN BIOPSIES, AND TRANSDUCED WITH A NON-REPLICATING, SELF-INACTIVATING LENTIVIRUS VECTOR THAT ENCODES HUMAN COLLAGEN TYPE VII ALPHA 1 (COL7A1) UNDER, (RECOMBINANT LENTIVIRUS VECTOR INXN-2004-TRANSDUCED HUMAN AUTOLOGOUS DYSTROPHIC EPIDERMOLYSIS BULLOSA DERMAL FIBROBLAST CELL FCX-007 INTEGRATED PROVIRAL HUMAN COLLAGEN TYPE VII TRANSGENE COL7A1 PLUS 5'
  3. Drug

    Selpercatinib

    go.drugbank.com/drugs/DB15685
    ApprovedInvestigational

    Selpercatinib is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes. … [A202055, A202052, L13604] Enhanced RET (Rearranged during transfection) oncogene expression is a hallmark of many cancers.

    Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile
  4. Drug

    Glycerin

    go.drugbank.com/drugs/DB09462
    ApprovedInvestigational

    A trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism.

    Mixtures: MICROLAX LAVMAN, 10 G, INTRALIPID 20%Categories: Cytochrome P-450 CYP2E1 Inducers, Cytochrome P-450 Enzyme Inducers
  5. Drug

    Phenylbutazone

    go.drugbank.com/drugs/DB00812
    ApprovedVet approvedWithdrawn

    It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication). … A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingSynonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione
  6. Target

    5-oxoprolinase

    go.drugbank.com/bio_entities/BE0002268
    TargetEnzymeHumans

    Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate

    Polypeptides: 5-oxoprolinaseSynonyms: 5-OPase, 5-oxo-L-prolinase
  7. Target

    Cadherin-5

    go.drugbank.com/bio_entities/BE0003403
    TargetHumans

    Cadherins are calcium-dependent cell adhesion proteins (By similarity). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types (Pu...

    Polypeptides: Cadherin-5
  8. Drug

    Plantago ovata seed

    go.drugbank.com/drugs/DB14585
    ApprovedWithdrawn

    Products: FYBOGEL ORANGE GRANÜL 3,5 G, 10 ADET, MUCOFALK ORANGE GRANÜL, 5 G
  9. Target

    Frizzled-5

    go.drugbank.com/bio_entities/BE0014104
    TargetHumans

    Receptor for Wnt proteins (PubMed:10097073, PubMed:20530549, PubMed:26908622, PubMed:9054360). Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling (By sim...

    Polypeptides: Frizzled-5Synonyms: Fz-5
  10. Drug

    Piperacillin

    go.drugbank.com/drugs/DB00319
    ApprovedInvestigational

    It is also used in combination with other antibiotics.

    Mixtures: TAZOJECT 2 G/ 0,25G IV ENJEKSIYONLUK LIYOFILIZE TOZ, 1 ADET, PIPERACILINA 4000 MG Y TAZOBACTAM 500 MGCategories: Penicillin G, Heterocyclic Compounds, 2-Ring