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Displaying results 3571 - 3580 of 10000 in total
  1. Target

    Inositol polyphosphate 5-phosphatase OCRL

    go.drugbank.com/bio_entities/BE0013933
    EnzymeHumans

    Also, is able to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate (PubMed:15474001, PubMed:40969890, PubMed:7761412). … Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic

    Polypeptides: Inositol polyphosphate 5-phosphatase OCRLSynonyms: Inositol polyphosphate 5-phosphatase OCRL-1, Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase
  2. Target

    Splicing factor 3B subunit 5

    go.drugbank.com/bio_entities/BE0018936
    TargetHumans

    Component of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:12234937, PubMed:27720643, PubMed:28781166, PubMed:32494006, PubMed:34822310). The 17S U2...

    Polypeptides: Splicing factor 3B subunit 5Synonyms: Pre-mRNA-splicing factor SF3b 10 kDa subunit
  3. Drug

    Salmeterol

    go.drugbank.com/drugs/DB00938
    ApprovedInvestigational

    Salmeterol is a long-acting beta-2 adrenergic receptor agonist drug that is currently prescribed for the treatment of asthma and chronic obstructive pulmonary disease COPD. … [L11545,L11548,L11551,L11554,L11557] It has a longer duration of action than the short-acting beta-2 adrenergic receptor agonist, [salbutamol].

    Mixtures: SERETIDE 50/100 ACCUHALER 50 mcg/100 mcg, ACTIONFLU® 100/50 MCGCategories: salmeterol and budesonide, salmeterol and fluticasone
  4. Drug

    Aluminum sulfate

    go.drugbank.com/drugs/DB11239
    Approved

    Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table [L2148]. … Medically, it is primarily used as a coagulating agent in minor cuts and abrasions as well as deodorant [L2144].

    Mixtures: DALIDOMEPOLVO SACHET 2.2 G, DOMEBORO® POLVOProducts: Sil Trax As No 10, Stingose Asp 373mg/ml
  5. Drug

    Pazopanib

    go.drugbank.com/drugs/DB06589
    ApprovedInvestigational

    Pazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.

    Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: VOTRIENT® 200 MG, VOTRIENT® 400 MG
  6. Drug

    Josamycin

    go.drugbank.com/drugs/DB01321
    Investigational

    A macrolide antibiotic from Streptomyces narbonensis. The drug has antimicrobial activity against a wide spectrum of pathogens.

    Categories: Macrolides, Lincosamides and StreptograminsSynonyms: leucomycin V 3-acetate 4B-(3-methylbutanoate), leucomycin V 3-acetate 4β-(3-methylbutanoate)
  7. Drug

    Choline

    go.drugbank.com/drugs/DB00122
    ApprovedInvestigationalNutraceutical

    A basic constituent of lecithin that is found in many plants and animal organs. … It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.

    Mixtures: Stress B With 1000 Mg Vitamin C, Prenatol-MCategories: Vitamin B Complex, Salicylic Acid and Derivatives
  8. Drug

    Clodronic acid

    go.drugbank.com/drugs/DB00720
    ApprovedInvestigationalVet approved

    Clodronic acid is a first generation bisphosphonate similar to [etidronic acid] and [tiludronic acid]. … [A203111] These drugs were developed to mimic the action of pyrophosphate, a regulator of calcification and decalcification.

    Categories: Drugs Affecting Bone Structure and MineralizationProducts: BONEFOS 800 MG TABLET, 60 ADET, Lodronat 520 mg - Filmtabletten
  9. Drug

    Tinzaparin

    go.drugbank.com/drugs/DB06822
    ApprovedInvestigational

    It is a heterogeneous mixture of with an average molecular weight between 5500 and 7500 daltons. … Tinzaparin is composed of molecules with and without a special site for high affinity binding to antithrombin III (ATIII). This complex greatly accelerates the inhibition of factor Xa.

    Categories: Heparin and similars, Blood and Blood Forming OrgansProducts: INNOHEP INYECTABLE VIAL 2 MG 10.000 UI/ML., INNOHEP INJECTION 14, 000 Anti-Xa IU/0.7ml
  10. Drug

    Mercaptopurine

    go.drugbank.com/drugs/DB01033
    ApprovedInvestigational

    It interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia.

    Categories: Antineoplastic and Immunomodulating Agents, Heterocyclic Compounds, 2-RingSynonyms: 6 MP, 6-MP