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START domain-containing protein 10
go.drugbank.com/bio_entities/BE0021582TransporterHumansMay play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl cha...
Polypeptides: START domain-containing protein 10Synonyms: StAR-related lipid transfer protein 10Doripenem
go.drugbank.com/drugs/DB06211ApprovedWithdrawnIn a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem carried an increased risk of death and lower clinical cure rates … , resulting in a premature termination of the trial.
Categories: Heterocyclic Compounds, 2-RingProducts: DOREXTRA® DORIPENEM 500 MG, REDIDOR 500 MG /VIAL5'-nucleotidase
go.drugbank.com/bio_entities/BE0001096TargetEnzymeHumansCatalyzes the hydrolysis of nucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside, with AMP being the preferred substrate (PubMed:21933152, PubMed:22997138, PubMed:23142347, PubMed:24887587, PubMed:344...
Polypeptides: 5'-nucleotidaseSynonyms: 5'-NT, 5'-deoxynucleotidaseInterleukin-5
go.drugbank.com/bio_entities/BE0001208TargetHumansHomodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed:2653458, PubMed:9010276). Also acts on activated and resting ...
Polypeptides: Interleukin-5Synonyms: IL-5Kallikrein-5
go.drugbank.com/bio_entities/BE0010708TargetHumansMay be involved in desquamation
Polypeptides: Kallikrein-5Primaquine
go.drugbank.com/drugs/DB01087ApprovedInvestigational(From Martindale, The Extra Pharmacopeia, 30th ed, p404) … It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria.
Categories: Heterocyclic Compounds, 2-Ring, P-glycoprotein inhibitorsSynonyms: 6-Methoxy-8-(4-amino-1-methylbutylamino)quinoline, 8-((4-Amino-1-methylbutyl)amino)-6-methoxyquinolineSulfaquinoxaline
go.drugbank.com/drugs/DB11464ExperimentalVet approvedSulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as
Products: TP-SQ 250 WSP Sulfaquinoxaline 250 mg/g Powder, Cocci-nil 45 mg/ml Oral SolutionDifluocortolone
go.drugbank.com/drugs/DB09095ApprovedWithdrawnIt was submitted to the FDA in July 1984 by the pharmaceutical company Schering AG.[L1082] … Difluocortolone is a potent topical corticosteroid. It is commonly used in dermatology for the reduction of inflammation and itching.
Mixtures: TİNAGEN 1 MG+10 MG/1 G DERİ KREMİ, 15 G, TRODERM 10 MG/G+1 MG/G KREM ,15 GCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersCalcium lactate
go.drugbank.com/drugs/DB13231ApprovedVet approvedCalcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common. … It is prepared commercially by the neutralization of lactic acid with calcium carbonate or calcium hydroxide.
Synonyms: Calcium 2-hydroxypropanoate (1:2), 2-Hydroxypropanoic acid calcium saltMixtures: FOSFO KALSIYUM GRANULE, 200 G, Calcium Lactate Et Magnesium SulfateSiltuximab
go.drugbank.com/drugs/DB09036ApprovedInvestigationalIt is administered as a 1 hour intravenous infusion every 3 weeks. … Siltuximab prevents the binding of IL-6 to soluble and membrane-bound IL-6 receptors by forming high affinity complexes with human interleukin-6 (IL-6).
Categories: Interleukin-6 Antagonist, Cytochrome P-450 CYP3A InducersProducts: SYLVANT 100 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN LİYOFİLİZE TOZ, 1 ADET, SYLVANT 400 MG İNFÜZYONLUK ÇÖZELTİ HAZIRLAMADA KULLANILACAK KONSANTRE İÇİN LİYOFİLİZE TOZ, 1 ADET