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Isradipine
go.drugbank.com/drugs/DB00270ApprovedIt exhibits greater selectivity towards arterial smooth muscle cells owing to alternative splicing of the alpha-1 subunit of the channel and increased prevalence of inactive channels in smooth muscle cells … It is structurally related to felodipine, nifedipine, and nimodipine and is the most potent calcium-channel blocking agent of the DHP class.
Categories: Antihypertensive Agents Indicated for HypertensionProducts: VASCAL UNO 5MG, VASCAL UNO MITECapsicum
go.drugbank.com/drugs/DB10897ApprovedCapsicum (Chili pepper) allergenic extract is used in allergenic testing.
Mixtures: Odynia-U, Mega Plex IV - PckCategories: Non-Standardized Food Allergenic Extract, Non-Standardized Plant Allergenic ExtractCrizanlizumab
go.drugbank.com/drugs/DB15271ApprovedInvestigational[A187907] Crizanlizumab, or SEG101, is given once every 4 weeks and may improve patient adherence. It was developed by Novartis and was granted FDA approval on November 15, 2019. … Crizanlizumab is a humanized IgG2 monoclonal antibody used to reduce the frequency of vaso-occlusive crises in patients with sickle cell disease.
Interferon alfacon-1
go.drugbank.com/drugs/DB00069ApprovedWithdrawnInterferon alfacon-1 is produced in Escherichia coli (E. coli) cells that have been genetically altered by insertion of a synthetically constructed sequence that codes for Interferon alfacon-1. … Interferon alfacon-1 is a recombinant non-naturally occurring type-I interferon.
Categories: Interferon Type ISynonyms: IFN-Con1, IFN Alfacon-1Fenoprofen
go.drugbank.com/drugs/DB00573ApprovedAn anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-NarcoticLemon
go.drugbank.com/drugs/DB10538ApprovedLemon allergenic extract is used in allergenic testing.
Mixtures: Megavite RxCategories: Non-Standardized Food Allergenic ExtractNisoldipine
go.drugbank.com/drugs/DB00401ApprovedNisoldipine may be used in alone or in combination with other agents in the management of hypertension. … Nisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Categories: Antihypertensive Agents Indicated for HypertensionInternational brands: Ji Ni Le Er, Baymycard RRGeraniol
go.drugbank.com/drugs/DB14183ApprovedThese pharmacologic effects are clinically important as geraniol is classified as generally-recognized-as-safe (GRAS) by the Flavor and Extract Manufacturers Association (FEMA) and the Food and Drug Administration … It is emitted from the flowers of many species of plant and is commonly used by the food, fragrance, and cosmetic industry[L3333].
Zimelidine
go.drugbank.com/drugs/DB04832ApprovedWithdrawnAdditionally, zimelidine was charged to cause an increase in suicidal ideation and/or attempts among depressive patients. … Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeCholine magnesium trisalicylate
go.drugbank.com/drugs/DB01401ApprovedCholine magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug.
Categories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Analgesics, Non-Narcotic