Search
Brimonidine
go.drugbank.com/drugs/DB00484ApprovedInvestigational[A178945] Thus brimonidine is an effective and safe alternative to beta-blockers, in patients with, or at high risk for, cardiopulmonary disease. … [A178951] It is considered to be a third generation alpha-2 aadrenergic receptor agonist, since it displays preferential binding at alpha-2 adrenoceptors over alpha-1 receptors.
Mixtures: Brim-Dor PF, Tim-Brim-Dor PFCategories: Sympathomimetics Used as DecongestantsCefaclor
go.drugbank.com/drugs/DB00833ApprovedInvestigationalSemisynthetic, broad-spectrum antibiotic derivative of cephalexin.
Products: CEFACLOR AL 250, CEFACLOR AL 500Polyvinyl alcohol
go.drugbank.com/drugs/DB11060ApprovedPolyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826]. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.
Categories: Compounds used in a research, industrial, or household settingProducts: ALCOHOL POLIVINILICO AL 1.4%, Polyvinyl Alcohol Eye Drops 1,4 % w/vDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … [A178741] Duloxetine first received approval from the FDA in August, 2004 as Cymbalta for the treatment of Major Depressive Disorder.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Ag-duloxetine, DULOXETIN AL 20MG KMRGalantamine
go.drugbank.com/drugs/DB00674ApprovedInvestigationalIt also acts as an allosteric modulator of the nicotinic receptor, giving its dual mechanism of action clinical significance. … [A1018] First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as _Galanthus nivalis_.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: GALANTAMIN AL 16MG HARTKAP, GALANTAMIN AL 24MG HARTKAPHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigationalHydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine]. … [L8072] It was developed during World War II as a derivative of [quinacrine] with less severe side effects.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Ag-hydroxychloroquineDarunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigationalDarunavir is a protease inhibitor used with other HIV protease inhibitor drugs as well as [ritonavir] for the effective management of HIV-1 infection. … [L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: DARUNAVIR AL 400MG FTA, DARUNAVIR AL 600MG FTAFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigationalIt works in a similar fashion as [dutasteride], which is another 5-alpha-reductase inhibitor, by exerting antiandrogenic effects. … Finasteride is a synthetic 4-azasteroid compound [L10565] and specific inhibitor of steroid Type II 5α-reductase, which is an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Ag-finasteride, Sandoz Finasteride AAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalAzithromycin [9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin] is a part of the _azalide_ subclass of macrolides, and contains a 15-membered ring, with a methyl-substituted nitrogen instead of a carbonyl … Azithromycin is a broad-spectrum macrolide antibiotic with a long half-life and a high degree of tissue penetration [A174172]. It was initially approved by the FDA in 1991 [A174175].
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: AZITHROMYCIN HEC P 200/5ML, Ag-azithromycinCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalCetirizine, also commonly known as _Zyrtec_, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal … One of the most common uses for this drug is for a condition called _allergic rhinitis_.
Mixtures: AZ-GRIP®DIACategories: P-glycoprotein inhibitors, P-glycoprotein substrates