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Displaying results 351 - 360 of 9682 in total
  1. Drug

    Sebelipase alfa

    go.drugbank.com/drugs/DB11563
    ApprovedInvestigational

    [L39337] Sebelipase alfa is a recombinant form LAL approved for the treatment of LAL deficiency. … In addition, patients with LAL deficiency typically develop dyslipidemia, which itself contributes to a number of adverse cardiovascular outcomes.

  2. Drug

    Triheptanoin

    go.drugbank.com/drugs/DB11677
    ApprovedInvestigational

    [A214812,A214817] Complications in lc-FAOD patients are reduced from approximately 60% to approximately 10% with the addition of triheptanoin. … Triheptanoin is a source of heptanoate fatty acids, which can be metabolized without the enzymes of long chain fatty acid oxidation.

  3. Drug

    Propylene glycol

    go.drugbank.com/drugs/DB01839
    ApprovedInvestigational

    A clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.

    Mixtures: SYSTANE HA SP SOLUCIÓN OFTÁLMICA, SYSTANE ® HA GOTAS OFTALMICAS LUBRICANTESCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Simeprevir

    go.drugbank.com/drugs/DB06290
    ApprovedWithdrawn

    Inhibiting HCV NS3/4A protease in a potent and highly specific manner, simeprevir is a direct-acting antiviral agent against the hepatitis C virus. … Like all NS3/4A inhibitors, simeprevir is a serine protease inhibitor in similarity to [DB08873] and [DB05521] but is classified as a second generation protease inhibitor.

    Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease Inhibitors
  5. Drug

    Butalbital

    go.drugbank.com/drugs/DB00241
    ApprovedIllicit

    [A177754] Butalbital has a low degree of selectivity and a narrow therapeutic index. … [L10370] Butalbital‐containing analgesics can also produce a drug‐induced headache in addition to tolerance and dependence.

    Mixtures: Vtol LQ, Alagesic LQ
  6. Drug

    Folic acid

    go.drugbank.com/drugs/DB00158
    ApprovedInvestigationalNutraceuticalVet approved

    This results in a deficiency of coenzymes and a resultant buildup of toxic substances that are responsible for numerous adverse side effects. … As a result, supplementation with 1-5mg of folic acid is recommended to prevent deficiency and a number of side effects associated with MTX therapy including mouth ulcers and gastrointestinal irritation

    Synonyms: Pteroyl-L-glutamate, Pteroyl-L-glutamic acidMixtures: Formula F L W, PNV 27-Ca/Fe/FA
  7. Drug

    Arbutin

    go.drugbank.com/drugs/DB11217
    Approved

    It has also been used as an anti-infective for the urinary system as well as a diuretic [F43]. … Extracted from the dried leaves of bearberry plant in the genus _Arctostaphylos_ and other plants commonly in the _Ericaceae_ family, arbutin is a beta-D-glucopyranoside of [DB09526].

    Mixtures: The Prestige BB SPF25 PA 2Plus, Absolute Total BB SPF37 PA 3PlusProducts: Dr Young 2p Brightening UV Sun Block SPF50 PA
  8. Drug

    Clioquinol

    go.drugbank.com/drugs/DB04815
    ApprovedVet approvedWithdrawn

    Clioquinol was withdrawn in 1983 due to neurotoxicity.

    Mixtures: Ala Quin, PRECORT-A KREM
  9. Drug

    D-alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14002
    ApprovedNutraceuticalVet approved

    Moreover, RRR-alpha-tocopherol acetate is a relatively stabilized form of vitamin E that is most commonly used as a food additive when needed [A32451]. … Nevertheless, vitamin E is known to be a fat-soluble antioxidant that has the capability to neutralize endogenous free radicals.

    Mixtures: Escavite Lq, Vitamin A C E W.niacinam.beta Car.and Min.Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers.

    Synonyms: (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline, [N2-[(S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-prolineMixtures: LISIPLUS AL 10MG/12.5MG, LISIPLUS AL 20MG/12.5MG