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Pantothenic acid
go.drugbank.com/drugs/DB01783ApprovedInvestigationalNutraceuticalVet approvedFor many animals, pantothenic acid is an essential nutrient as it is required to synthesize coenzyme-A (CoA), as well as to synthesize and metabolize proteins, carbohydrates, and fats. … Pantothenic acid is the amide between pantoic acid and β-alanine and commonly found as its alcohol analog, the provitamin panthenol, and as calcium pantothenate.
Mixtures: B Compound 50mg Tab, D Pantothenic 500mg With 100mg CProducts: Vitamin B5 Tab 50mg USP Chewable, Calpan Tab 100mgLacosamide
go.drugbank.com/drugs/DB06218ApprovedInvestigational[A262681] It was granted approval by Health Canada in September 2010.[L49206] … As a chiral functionalized amino acid, it works by blocking slowly inactivating components of voltage-gated sodium currents.
Products: BENVIDA 10MG/ML ŞURUP, 200 ML, VIMPAT JARABE 15MG/MLSumatriptan
go.drugbank.com/drugs/DB00669ApprovedInvestigational[A179761] Sumatriptan was granted FDA approval on 28 December 1992.[L6805] … [L6793,L6796,L6799,L6805,L6808,L6811] Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines.
International brands: Boots Pharmacy Migraine ReliefProducts: Imitrex Df - Tab 25mg, Imitrex Inj 12mg/mlFexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigational[L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … antihistamines, such as [diphenhydramine], which readily bind to off-targets that contribute to side effects such as sedation.
Products: TELFAST 180MG, EXODIN TABLET 180MGTerbutaline
go.drugbank.com/drugs/DB00871ApprovedInvestigational[A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088] … Terbutaline was first synthesized in 1966[A230333] and described in the literature in the late 1960s and early 1970s.
Mixtures: BRICANYL EX, ULTRABRON T JARABEProducts: TERBUTALINA 10MG / ML SOLUCION PARA NEBULIZACION, PHARMANIAGA TERBUTALINE RESPIRATOR SOLUTION 10MG/MLAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalIt is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
Products: SAPHRIS SUBLINGUAL TABLET 10MG, SYCREST 10MG DILALTI TABLET, 100 TABLETClofarabine
go.drugbank.com/drugs/DB00631ApprovedInvestigationalIt is marketed as Clolar in the U.S. and Canada, or Evoltra in Europe, Australia, and New Zealand. … It is not known if the drug extends life expectancy. Its potential use in acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) has been investigated.
Products: CLOFAZIC® 20MG/20ML, METISA® 1MG /MLBumetanide
go.drugbank.com/drugs/DB00887ApprovedInvestigationalBumetanide is a sulfamyl diuretic.
Categories: Increased Diuresis at Loop of HenleProducts: BUMET 1MG TABLET, BURINEX TABLET 1MGSuccinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigational[A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures.
Products: Anectine Inj 20mg/ml, Quelicin Inj 20mg/ml USPLithium carbonate
go.drugbank.com/drugs/DB14509ApprovedInvestigationalLithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. … Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Products: PMS-lithium Carbonate - Cap 150mg, Pal-lithium Carbonate