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Alverine
go.drugbank.com/drugs/DB01616ApprovedInvestigationalWithdrawnIt can also be used to help relieve period pain. … Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions.
Categories: Alimentary Tract and MetabolismSynonyms: N,N-Bis(3-phenylpropyl)ethylamine, N-Ethyl-N-(3-phenylpropyl)benzenepropanaminePlecanatide
go.drugbank.com/drugs/DB13170ApprovedInvestigationalIt should not be used in children less than six years of age, and should be avoided in patients six years to 18 years of age … Plecanatide is a drug approved in January 2017 by the FDA for the treatment of chronic idiopathic constipation (CIC).
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsOlive oil
go.drugbank.com/drugs/DB09567ApprovedInvestigationalUsed as a source of fatty acids in total parenteral nutrition and as an additive in some cosmetic products [FDA Label]. … Consists primarily of the glycerides of the fatty acids linoleic, oleic and palmitic.
Mixtures: CLINOLEIC %20 IV İNFÜZYONLUK LİPİD EMÜLSİYON, 100 ML, CLINOLEIC %20 IV İNFÜZYONLUK LİPİD EMÜLSİYON, 250 MLCategories: Diet, Food, and NutritionUC-781
go.drugbank.com/drugs/DB05871InvestigationalUC-781 is a thiocarboxanilide non-nucleoside reverse transcriptase inhibitor (NNRTI). It is a topical microbicide targeted against the AIDS virus.
Ornithine
go.drugbank.com/drugs/DB00129ApprovedInvestigationalNutraceuticalProduced during the urea cycle, ornithine is an amino acid produced from the splitting off of urea from arginine. … L-Ornithine allows for the disposal of excess nitrogen and acts as a precursor of citrulline and arginine.
Mixtures: Primene 10%-liq IVCategories: Bile and Liver Therapy, Alimentary Tract and MetabolismBenzhydrocodone
go.drugbank.com/drugs/DB15465ApprovedIt was first approved by the FDA in February 2018 in combination with [acetaminophen] under the trade name Apadaz, marketed by KVK Tech and developed by KemPharm.[L7859,L7862] … Benzhydrocodone is a benzylic prodrug of hydrocodone.[L4894] It was developed in an effort to reduce parenteral bioavailability of the active metabolite as a deterrent to abuse.
Mixtures: Benzhydrocodone and Acetaminophen, Benzhydrocodone and AcetaminophenClascoterone
go.drugbank.com/drugs/DB12499ApprovedInvestigational[A218846] In August 2020, FDA approved clascoterone for the first-in-class topical treatment of acne (acne vulgaris) in male and female patients 12 years and older. … proliferation, excess sebum production, and inflammatory pathways.
Categories: Hormones, Hormone Substitutes, and Hormone AntagonistsRisdiplam
go.drugbank.com/drugs/DB15305ApprovedInvestigationalRisdiplam is an orally bioavailable mRNA splicing modifier used for the treatment of spinal muscular atrophy (SMA). … [L15351,A216871] Risdiplam was approved by the FDA in August 2020 for the treatment of spinal muscular atrophy (SMA).
Filgotinib
go.drugbank.com/drugs/DB14845ApprovedInvestigationalRheumatoid arthritis (RA) is a chronic, autoimmune, systemic, and inflammatory disease that causes synovial joint symptoms and can limit range of motion in severe cases. … [A189165] JAK2 and JAK3 play important roles in both immune and hematologic functions; therefore, selectivity for JAK1 aims to improve the safety profile of filgotinib while maintaining clinical efficacy
Categories: Antineoplastic and Immunomodulating AgentsTolrestat
go.drugbank.com/drugs/DB02383ApprovedWithdrawnIt was sold under the tradename Alredase but was discontinued by Wyeth in 1997 because of the risk of severe liver toxicity and death. … Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications.
Categories: Drugs Used in Diabetes, Alimentary Tract and Metabolism