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Amitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. Amitriptyline has been investigated in...
Gadoteridol
go.drugbank.com/drugs/DB00597ApprovedInvestigationalGadoteridol is a macrocyclic nonionic gadolinium that provides contrast enhancement of the brain, spine, and surrounding tissues, resulting in improved visualization (compared with unenhanced MRI) of lesions with abnormal vascularity or ...
Tetrahydrocannabivarin
go.drugbank.com/drugs/DB11755InvestigationalFurther evidence has also shown that THCV acts as an agonist of GPR55 and l-α-lysophosphatidylinositol (LPI) [A32974]. … Δ9-THC is currently available in several synthetic forms, including [Dronabinol], while purified or isolated THCV is not approved for any medical uses and is not available as any marketed products.
Tepoxalin
go.drugbank.com/drugs/DB11466ExperimentalVet approvedIt is primarily used to reduce inflammation and relief of pain caused by musculoskeletal disorders such as hip dysplasia and arthritis.
Methylmethionine chloride
go.drugbank.com/drugs/DB13250ExperimentalIn Japan, it is used as an over the counter product for gastrointestinal health support. It is also called "Vitamin U", but it is not a true vitamin.
Dihydroxyacetone
go.drugbank.com/drugs/DB01775ExperimentalIn combination with naphthoquinones it acts as a sunscreening agent. [PubChem]
Gentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A233325,A234359,A234364] There is the added benefit of synergy when gentamicin is co-administered with other antibacterials such as beta-lactams.
Talacotuzumab
go.drugbank.com/drugs/DB14796InvestigationalTalacotuzumab is an IgG1 monoclonal antibody directed toward the IL3 receptor α–subunit, also known as CD123.
AMY-101
go.drugbank.com/drugs/DB14803InvestigationalAMY-101, also known as compstatin 40, is a peptidic inhibitor of the central complement component C3.
Pegcrisantaspase
go.drugbank.com/drugs/DB16281InvestigationalPegcrisantaspase is under investigation in clinical trial NCT02257684 (A Dose Confirmation and Pharmacokinetic Study of Pegcrisantaspase Administered as Intravenous (IV) Infusion in Children and Young