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Polydatin
go.drugbank.com/drugs/DB11263ApprovedWhile it is isolated from the bark of *Picea sitchensis* or *Polygonum cuspidatum*, polydatin may be detected in grape, peanut, hop cones, red wines, hop pellets, cocoa-containing products, chocolate products … It is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis [A27229].
Synonyms: Polydatin (E)-isomerAxitinib
go.drugbank.com/drugs/DB06626ApprovedInvestigationalIt is reported to exhibit potency that is 50-450 times higher than that of the first generation VEGFR inhibitors.[L6676] Axitinib is an indazole derivative. … [A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations.
Synonyms: N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamideGramicidin D
go.drugbank.com/drugs/DB00027ApprovedInvestigationalGramcidins are 15 residue peptides with alternating D and L amino acids, which assemble inside of the hydrophobic interior of the cellular lipid bilayer to form a β-helix. … Gramcidin D is a heterogeneous mixture of three antibiotic compounds, gramicidins A, B and C, making up 80%, 6%, and 14% respectively all of which are obtained from the soil bacterial species Bacillus
Cefotetan
go.drugbank.com/drugs/DB01330ApprovedInvestigationalThe drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative microorganisms.
Batroxobin
go.drugbank.com/drugs/DB09005InvestigationalIn addition to batroxobin, the venom of Bothrops atrox has a composition of 10.2% neutral carbohydrate. Batroxobin is a serine protease, which cleaves the 16 Arginine - 17 Glycine bond in fibrinogen. … Once bound to fibrin, it will cause fibrin accretion(clot formation) to a degree 18 folds greater than thrombin.
International brands: Su Le JuanEquilin
go.drugbank.com/drugs/DB02187ExperimentalIt has a total of four double bonds in the A- and B-ring. High concentration of equilin is found in the urine of pregnant mares.
Sesame oil
go.drugbank.com/drugs/DB11172ApprovedNutraceuticalSesame oil is reported to possess antioxidant, antiaging, antihypertensive, immunoregulatory and anticancer properties. It has also shown to accelerate alcohol decomposition in the liver [A27257]. … Sesame oil is considered an indirect additive used in food cotact substances by the FDA.
Phosphate ion
go.drugbank.com/drugs/DB14523InvestigationalMixtures: PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1000 ML, PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1500 ML2,5-Dimethoxy-4-ethylamphetamine
go.drugbank.com/drugs/DB01467ExperimentalIllicitCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome