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Phorbol 12-myristate 13-acetate diester
go.drugbank.com/drugs/DB17045InvestigationalPhorbol 12-myristate 13-acetate diester is an inducer of neutrophil extracellular traps (NETs).[A253087]
Vidutolimod
go.drugbank.com/drugs/DB17500InvestigationalIt is an investigational cancer vaccine.
Synonyms: Dna, d(g-g-g-g-g-g-g-g-g-g-g-a-c-g-a-t-c-g-t-c-g-g-g-g-g-g-g-g-g-g)AAV-CNGB3
go.drugbank.com/drugs/DB18344InvestigationalAAV-CNGB3 is an adenovirus associated viral vector serotype 8 containing the human CNGB3 gene.
Duvoglustat
go.drugbank.com/drugs/DB03206InvestigationalAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
Synonyms: D-1-deoxynojirimycin, 1,5-deoxy-1,5-imino-D-mannitolMecasermin rinfabate
go.drugbank.com/drugs/DB14751ApprovedInvestigationalMecasermin rinfabate is approved for severe primary insulin-like growth factor (IGF) deficiency or in patients with GH gene deletion who have developed antibodies to growth hormone (GH) . Mecasermin rinfabate is similar to DB01277 in tha...
Pralsetinib
go.drugbank.com/drugs/DB15822ApprovedInvestigationalPralsetinib, similar to the previously approved selpercatinib, is a kinase inhibitor with enhanced specificity for RET tyrosine kinase receptors (RTKs) over other RTK classes. Enhanced RET (Rearranged during transfection) oncogene expres...
Crotalus atrox antivenin
go.drugbank.com/drugs/DB13892ApprovedEach year it is estimated there are 45,000 snakebites in the US and 300,000 to 400,000 bites worldwide. About 8000 of these snakebites involve venomous snake species. The majority of people bitten are males and about 50% occur in the age...
Ethionamide
go.drugbank.com/drugs/DB00609ApprovedInvestigationalWithdrawnA second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Clofibrate
go.drugbank.com/drugs/DB00636ApprovedWithdrawnA fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p986)
Mexiletine
go.drugbank.com/drugs/DB00379ApprovedInvestigationalAntiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.