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Cocaine
go.drugbank.com/drugs/DB00907ApprovedIllicitInvestigationalIt also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. … It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl esterNeratinib
go.drugbank.com/drugs/DB11828ApprovedInvestigationalNeratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer.
Categories: Heterocyclic Compounds, 2-Ring, Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitorsSynonyms: 奈拉替尼Fenyramidol
go.drugbank.com/drugs/DB13414InvestigationalCategories: Heterocyclic Compounds, 1-RingProducts: CABRAL 400 MG 24 DRAJE, CABRAL 400 MG FİLM TABLET, 24 ADETAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalIt is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009. … Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with
Categories: Adrenergic alpha-1 Receptor Antagonists, Serotonin 5-HT1 Receptor AntagonistsProducts: SYCREST 5MG DILALTI TABLET, TABLET, 20 ADET, SYCREST 10MG DILALTI TABLET, TABLET, 20 ADETApraclonidine
go.drugbank.com/drugs/DB00964ApprovedInvestigationalApraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Categories: Adrenergic alpha-2 Receptor Agonists, Heterocyclic Compounds, 1-RingSynonyms: 4-AminoclonidineApalutamide
go.drugbank.com/drugs/DB11901ApprovedInvestigationalApproximately 10 to 20 % of prostate cancer cases are castration-resistant, and up to 16% of these patients show no evidence of cancer metastasis at the time of castration-resistant diagnosis [L1295]. … In a phase-2 multicenter open-label study, 89% of patients with non-metastatic, castration-resistant prostate cancer had ≥50% PSA decline at week 12 of apalutamide treatment [A31846].
Categories: MATE 2 Inhibitors, MATE 1 InhibitorsProducts: ERLEADA ®TABLETAS RECUBIERTAS 60 MGTetrofosmin
go.drugbank.com/drugs/DB11180ApprovedIt presents a molecular formula of 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane. Tetrofosmin is part of the group of diphosphines. … Tetrofosmin is used in conjunction with technetium Tc-99m as a radiopharmaceutical.[A7788]
Mixtures: Tetrofosmin ROTOP 0,23 mg Kit für ein radioaktives ArzneimittelCategories: P-glycoprotein substratesMesterolone
go.drugbank.com/drugs/DB13587InvestigationalIt is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. … Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT).
Categories: 5-Androstanon (3) DerivativesProducts: PROVIRON 25 MG TABLET, 20 ADET, RESTORE TABLET 25 mgOxidronic acid
go.drugbank.com/drugs/DB14159ApprovedSynonyms: HMD-PProducts: TECHNESCAN HDP FOR INJECTION 3 mg/vial, TECHNESCAN HDP POWDER FOR INJECTION 3.15 mg/vialDalbavancin
go.drugbank.com/drugs/DB06219ApprovedInvestigationalpyogenes, S. agalactiae, S. dysgalactiae, the S. anginosus group (including S. anginosus, S. intermedius, and S. constellatus), and Enterococcus faecalis (vancomycin susceptible strains) [FDA Label, F2356 … Dalbavancin acts by interfering with bacterial cell wall synthesis by binding to the D-alanyl-D-alanine terminus of nascent cell wall peptidoglycan and preventing cross-linking [FDA Label, F2356, A4072
Products: Dalbavancin Accord 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung, Dalbavancin ratiopharm 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung