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Displaying results 3631 - 3640 of 5451 in total
  1. Drug

    Liothyronine

    go.drugbank.com/drugs/DB00279
    ApprovedInvestigationalVet approved

    Liothyronine is a thyroidal hormone T3 which is normally produced by the thyroid gland in a ratio 4:1 when compared with T4: T3. Liothyronine is the active form of thyroxine which is composed in a basic chemical structure by a tyrosine w...

  2. Drug

    Spirapril

    go.drugbank.com/drugs/DB01348
    ApprovedInvestigational

    Spirapril is an ACE inhibitor antihypertensive drug used to treat hypertension. Spirapril is converted to the active spiraprilat after administration. ACE inhibitors are used primarily in treatment of hypertension and congestive heart fa...

  3. Drug

    Trichloroethylene

    go.drugbank.com/drugs/DB13323
    Approved

    It has been sold under a variety of trade names including Trimar and Trilene and used as a volatile anesthetic and as an inhaled obstetrical analgesic.

  4. Drug

    Tradipitant

    go.drugbank.com/drugs/DB12580
    ApprovedInvestigational

    Tradipitant is a selective, high-affinity antagonist at human substance P/neurokinin-1 (NK-1) receptors.

  5. Drug

    Tagatose

    go.drugbank.com/drugs/DB04936
    Investigational

    It is approved as a food additive as a low calorie sweetener. Additionally, it is under investigation by Spherix for the treatment of obesity and type II diabetes. … It is a naturally occurring monosaccharide, specifically a hexose. It is commonly found in dairy with a similar texture and sweetened capacity to sucrose but with only a third of the calories.

  6. Drug

    Cyclopropane

    go.drugbank.com/drugs/DB13984
    Experimental

    Instead, it turned out to be an excellent anesthetic with very rapid onset and recovery while maintaining stable hemodynamics. Its use was ultimately limited because it was highly explosive. … Cyclopropane was initially investigated because it was thought to be the toxic element in ethylene.

  7. Drug

    Dicyclomine

    go.drugbank.com/drugs/DB00804
    ApprovedInvestigational

    [A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small amount of evidence and so its prescription is becoming less favourable.

    Products: RELESTAL PEDIATRIC SYRUP 10 mg/5 ml
  8. Drug

    Talazoparib

    go.drugbank.com/drugs/DB11760
    ApprovedInvestigational

    [L47296] It was approved by Health Canada in September 2020.[L47301] Talazoparib is currently used in the treatment of BRCA-mutated breast cancer and HRR-mutated prostate cancer.

    Products: TALZENNA CAPSULE 1MG, Talzenna 1mg Hard Capsules
  9. Drug

    Oleandomycin

    go.drugbank.com/drugs/DB11442
    ExperimentalVet approved

    Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of _Streptomyces antibioticus_.

  10. Drug

    Oteseconazole

    go.drugbank.com/drugs/DB13055
    ApprovedInvestigational

    Oteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51. CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes. By bin...

    Synonyms: VT-1161