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Hesperetin

Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside [hesperidin], is the predominant flavonoid in lemons and oranges.

CZEN 002

The antimicrobial activity of CZEN-002 is unique in that it does not depend on direct damage to the microbial membrane. … A second focus was on the sequence Lys-Pro-Val (11-13) that is known to be important for antimicrobial activity.

Aleglitazar

Aleglitazar is an agonist at the peroxisome proliferator-activated receptor (PPAR) for both the PPARα and PPARγ receptor subtypes. … In the phase II clinical trial called SYNCHRONY, with type II diabetic patients, aleglitazar was able to control both lipid and glucose levels in a synergistic manner while also having limited side effects

Bicifadine

Bicifadine was shown to have potent analgesic activity in vivo and was chosen for further development for the treatment of pain. … It is an inhibitor of both the norepinephrine and serotonin transporters and an NMDA antagonist with a non-narcotic profile.

Fibroblast growth factor-1

Ketanserin

Ketanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.

Desoximetasone

A topical anti-inflammatory glucocorticoid used in dermatoses, skin allergies, psoriasis, etc.

Doxylamine

Histamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.

Glutethimide

Glutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs.

Talmapimod

Talmapimod is the first-generation oral p38 MAP kinase inhibitor developed by Scios. It has shown to be effective to cure inflammatory diseases such as Rheumatoid Arthritis.