Search

Displaying results 3651 - 3660 of 9705 in total
  1. Drug

    Margetuximab

    go.drugbank.com/drugs/DB14967
    ApprovedInvestigational

    Of the various subtypes of breast cancer, HER2-positive breast cancer is characterized by _ERBB2_ overexpression, a higher grade, a more aggressive phenotype, and a worse prognosis compared to HER2-negative … The HER2 oncoprotein, the product of the human _ERBB2_/mouse _neu_ genes, is a member of the HER family of receptor tyrosine kinases that includes the epidermal growth factor receptor (EGFR).

  2. Drug

    Alobresib

    go.drugbank.com/drugs/DB14970
    Investigational

    Alobresib is under investigation in clinical trial NCT02607228 (Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GS-5829 as a Single Agent and In Combination With Enzalutamide in Participants

  3. Drug

    IMCY-0141

    go.drugbank.com/drugs/DB17019
    Investigational

    IMCY-0141 is a synthetic peptide based on MOG (Myelin Oligodendrocyte Glycoprotein), a dominant autoantigen, designed to stop the progression of multiple sclerosis (MS) and the destruction of the myelin

  4. Drug

    NSC-663284

    go.drugbank.com/drugs/DB17038
    Experimental

    NSC-663284 is a potent quinolinedione Cdc25 phosphatase inhibitor.[A253052]

  5. Drug

    PIK-75

    go.drugbank.com/drugs/DB17047
    Experimental

    PIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097]

    Synonyms: Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazide
  6. Drug

    Plumbagin

    go.drugbank.com/drugs/DB17048
    Investigational

    Plumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    RS-39604

    go.drugbank.com/drugs/DB17050
    Experimental

    RS-39604 is a selective 5-HT4 receptor antagonist.[A253112]

  8. Drug

    SB-218078

    go.drugbank.com/drugs/DB17051
    Experimental

    SB-218078 is a specific inhibitor of CHK1.[A253117]

  9. Drug

    Scriptaid

    go.drugbank.com/drugs/DB17053
    Experimental

    Scriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.[A253127]

  10. Drug

    SKF-96365 free base

    go.drugbank.com/drugs/DB17054
    Experimental

    SKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.[A253132]