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Displaying results 3651 - 3660 of 10000 in total
  1. Drug

    Carisoprodol

    go.drugbank.com/drugs/DB00395
    Approved

    In January 2012, this drug was classified as a Schedule IV substance under the controlled substances act in several US states due to alarming rates of abuse [A176062, A176077] despite having a low potential … for abuse in addition to a low risk of dependence [L5074].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesSynonyms: N-isopropy-2-methyl-2-propyl-1,3-propanediol dicarbamate, (1-methylethyl)carbamic acid 2-(((aminocarbonyl)oxy)methyl)-2-methylpentyl ester
  2. Drug

    Ifinatamab deruxtecan

    go.drugbank.com/drugs/DB18212
    Investigational

    Synonyms: -CHAIN, DIMER, THIOETHER WITH N-(6-(3-MERCAPTO-2,5-DIOXO-1-PYRROLIDINYL)-1-OXOH, IMMUNOGLOBULIN G1, ANTI-(HUMAN B7 HOMOLOG 3 PROTEIN) (HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL MABX-9001A .KAPPA.
  3. Drug

    Dextrose, unspecified form

    go.drugbank.com/drugs/DB09341
    ApprovedInvestigationalVet approved

    L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. … Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature.

    Mixtures: GLUCOSA AL 5% EN SOLUCION DE CLORURO DE SODIO AL 0.9%, CLORURO DE POTASIO 20 mEq EN DEXTROSA AL 5% Y CLORURO DE SODIO AL 0.45% BAXTERCategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Udifitimod

    go.drugbank.com/drugs/DB19053
    Investigational

    Udifitimod is under investigation in clinical trial NCT05014438 (A Study of BMS-986166 or Branebrutinib for the Treatment of Participants With Atopic Dermatitis).

    Synonyms: ((1R,3S)-1-amino-3-((S)-6-(2-methoxyphenethyl)-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopentyl)methanol, [(1R,3S)-1-amino-3-{(6S)-6-[2-(2-methoxyphenyl)ethyl]- 5,6,7,8-tetrahydronaphthalen-2-yl}cyclopentyl]methanol
  5. Drug

    AZD-7268

    go.drugbank.com/drugs/DB19203
    Investigational

    AZD-7268 is under investigation in clinical trial NCT01020799 (AZD7268 Safety and Tolerability Study).

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: Benzamide, n-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-, N-(2-hydroxyethyl)-n-methyl-4-(8-quinolinyl(1-(4-thiazolylmethyl)-4-piperidinylidene)methyl)-benzamide
  6. Drug

    Zebularine

    go.drugbank.com/drugs/DB03068
    Experimental

    A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. … Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-beta-D-ribofuranosyl-2(1H)-pyrimidinone, 1-beta-D-ribofuranosylpyrimidin-2(1H)-one
  7. Drug

    Flumazenil

    go.drugbank.com/drugs/DB01205
    ApprovedInvestigational

    Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine … receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.

    Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 2-RingProducts: ANEXATE 1 MG/10 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET, ANEXATE 0,5 MG/5 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET
  8. Drug

    Tetramethylpyrazine nitrone

    go.drugbank.com/drugs/DB23609
    Investigational

    Synonyms: (Z)-N-TERT-BUTYL-1-(3,5,6-TRIMETHYLPYRAZIN-2-YL)METHANIMINE OXIDE, N-TERT-BUTYL-1-(3,5,6-TRIMETHYLPYRAZIN-2-YL)METHANIMINE OXIDECategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Dopamine

    go.drugbank.com/drugs/DB00988
    ApprovedInvestigational

    Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (receptors, dopamine) mediate its action. … One of the catecholamine neurotransmitters in the brain. It is derived from tyrosine and is the precursor to norepinephrine and epinephrine.

    Mixtures: INYECCION DE CLORHIDRATO DE DOPAMINA EN DEXTROSA AL 5% USP (1600 MCG/ML), INYECCION DE CLORHIDRATO DE DOPAMINA 800 MCG/ML DEXTROSA AL 5% UPSCategories: Compounds used in a research, industrial, or household setting, Selective Beta 1-adrenergic Agonists
  10. Drug

    Somatotropin

    go.drugbank.com/drugs/DB00052
    ApprovedInvestigational

    [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa. … [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names.

    Mixtures: Nutropin - Kit Pws(5mg) & Liq(10ml) Im ScCategories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inducers