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Ribociclib
go.drugbank.com/drugs/DB11730ApprovedInvestigationalRibociclib is a selective cyclin-dependent kinase inhibitor, a class of drugs that help slow the progression of cancer by inhibiting two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6).
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: KISQALI (200 MG), KISQALI 200 MG TABLETAS RECUBIERTASBaloxavir marboxil
go.drugbank.com/drugs/DB13997ApprovedInvestigational[L4779] It was also approved by the European Commission on January 7, 2021.[L45241] … More specifically, it is a first-in-class cap-dependent endonuclease inhibitor that works to block influenza virus proliferation.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: XOFLUZA 40 MG FİLM KAPLI TABLET, 1 ADET, XOFLUZA 20 MG FİLM KAPLI TABLET, 2 ADETEmedastine
go.drugbank.com/drugs/DB01084ApprovedEmedastine is an antihistamine used in eye drops to treat allergic conjunctivitis.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 1-(2-Ethoxy-ethyl)-2-(4-methyl-[1,4]diazepan-1-yl)-1H-benzoimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzimidazoleCardiolipin Biosynthesis CL(10:0/10:0/10:0/10:0)
smpdb.ca/view/SMP0175274MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition. It is essential for the optimal function of numerous enzymes that are involved in mitochondrial...
Afatinib
go.drugbank.com/drugs/DB08916ApprovedInvestigationalAfatinib is a 4-anilinoquinazoline tyrosine kinase inhibitor in the form of a dimaleate salt available as Boehringer Ingelheim's brand name Gilotrif [FDA Label]. … For oral use, afatinib tablets are a first-line (initial) treatment for patients with metastatic non-small cell lung cancer (NSCLC) with common epidermal growth factor receptor (EGFR) mutations as detected
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: GIOTRIF® 50 MG, GIOTRIF® 30 MGEthionamide
go.drugbank.com/drugs/DB00609ApprovedInvestigationalWithdrawnA second-line antitubercular agent that inhibits mycolic acid synthesis. It also may be used for treatment of leprosy. (From Smith and Reynard, Textbook of Pharmacology, 1992, p868)
Synonyms: ETH, ETPCategories: Heterocyclic Compounds, 1-RingHydrocortisone acetate
go.drugbank.com/drugs/DB14539ApprovedInvestigationalVet approvedSynonyms: 21-O-acetylcortisolMixtures: KORTOS 27 MG/5 MG SUPOZİTUVAR, 10 ADET, UREACORT YAĞLI %0,5 + %10 KREM (30 G)Hydrogen peroxide
go.drugbank.com/drugs/DB11091ApprovedInvestigationalVet approvedIt is used in industrial and cosmetic applications as a bleaching agent. … As a natural product of metabolism, it readily undergoes decomposition by catalase in normal cells [L2024].
Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household settingTiamulin
go.drugbank.com/drugs/DB11468ExperimentalVet approvedTiamulin is a pleuromutilin antibiotic drug that is used in veterinary medicine particularly for pigs and poultry.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 CYP2E1 InhibitorsProducts: Triamulox 800 mg/g Granular, Biomutin 200 mg/ml Solution for InjectionBrompheniramine
go.drugbank.com/drugs/DB00835ApprovedHistamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Synonyms: 1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane, 3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamineMixtures: Bio T Pres-B, M-end Wc