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Voretigene neparvovec
go.drugbank.com/drugs/DB13932ApprovedInvestigational[A31478] VN-rzyl was developed by Spark Therapeutics Inc. and FDA approved on December 19, 2017.[L1095] … When used in genetic therapy, this virus is modified for the elimination of its negligible integrative capacity by the removal of *rep* and *cap* and the insertion of the desired gene with its promoter
Durlobactam
go.drugbank.com/drugs/DB16704ApprovedInvestigationalIt is typically given in combination with [sulbactam] to protect it from degradation by certain serine-beta-lactamases. … [A263306] It is used to treat hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP), caused by susceptible isolates of _Acinetobacter baumannii-calcoaceticus_
Synonyms: (2S,5R)-2-CARBAMOYL-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL SULFATE, SULFURIC ACID, MONO((2S,5R)-2-(AMINOCARBONYL)-3-METHYL-7-OXO-1,6-DIAZABICYCLO(3.2.1)OCT-3-EN-6-YL) ESTERCOVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection
go.drugbank.com/drugs/DB16520ExperimentalPresentation Therapeutic Biologics (COVID-19--AP) (AP-TP-Bio))[L31333]. … COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection is an intradermal injection currently being investigated in the clinical trial NCT03348670 (Discovery Stage (Proof-of-concept) COVID-19 Antigen
Synonyms: COVID-19 Spike-GM-CSF Protein Lactated Ringer's Injection, COVID-19 Therapeutic Biologics - Spike-GM-CSF Protein Lactated Ringer's InjectionDicirenone
go.drugbank.com/drugs/DB20938ExperimentalThe usage of the INN stem '-renone' in the name indicates that Dicirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.
Atrasentan
go.drugbank.com/drugs/DB06199ApprovedInvestigationalto be approved for this condition. … [L52855] In April 2025, atrasentan was granted accelerated approval by the FDA for the reduction of proteinuria in patients with primary IgA nephropathy, becoming the first endothelin A receptor antagonist
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP2B6 InhibitorsAsparagine
go.drugbank.com/drugs/DB00174ApprovedNutraceuticalWithdrawnIt is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Mixtures: AMINOPLASMAL-10% E INFUSION, AMINOPLASMAL HEPA 10%-500ML GLASS BOTTLETumor necrosis factor receptor superfamily member 16
go.drugbank.com/bio_entities/BE0010540TargetHumansLow affinity receptor which can bind to NGF, BDNF, NTF3, and NTF4. … to the regulation of insulin-dependent glucose uptake (By similarity).
Polypeptides: Tumor necrosis factor receptor superfamily member 16Acetylcholine receptor subunit alpha-type acr-16
go.drugbank.com/bio_entities/BE0027703TargetCaenorhabditis elegansAfter binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity
Polypeptides: Acetylcholine receptor subunit alpha-type acr-16Pentastarch
go.drugbank.com/drugs/DB09111ApprovedWithdrawnPentastarch is characterized by presenting five hydroxyethyl groups, which signifies an approximate 50% hydroxyethylation. … It is sold under the name Pentaspan by Bristol-Myers Squibb and is used for fluid resuscitation.
Products: HESTAR-200