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Displaying results 3671 - 3680 of 8974 in total
  1. Drug

    Talimogene laherparepvec

    go.drugbank.com/drugs/DB13896
    ApprovedInvestigational

    It was approved by the FDA in 2015 under the market name Imlygic. In general, talimogene laherparepvec has been modified so that it can infect and multiply inside melanoma cells [L2221]. … Alternatively, although talimogene laherparepvec also enters healthy cells, it is not designed to multiply inside them [L2221].

    Synonyms: T Vec, T-Vec
  2. Drug

    Amylocaine

    go.drugbank.com/drugs/DB09088
    ApprovedWithdrawn

    Although amylocaine could be administered topically or injected, it was most widely used for spinal anesthesia [L1882]. … Elsewhere in English speaking countries it was referred to as Stovaine, given the meaning of the French word 'fourneau' as 'stove' in English [L1882].

  3. Drug

    Rimantadine

    go.drugbank.com/drugs/DB00478
    Approved

    An RNA synthesis inhibitor that is used as an antiviral agent in the prophylaxis and treatment of influenza.

    Categories: Antiinfectives for Systemic Use
  4. Drug

    Estrone

    go.drugbank.com/drugs/DB00655
    Approved

    Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase. … It is produced in vivo from androstenedione or from testosterone via estradiol.

  5. Drug

    Salix alba bark

    go.drugbank.com/drugs/DB14274
    Approved

    Salix alba bark is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: Quick-Acting Wart Removal
  6. Drug

    Tetraethylammonium

    go.drugbank.com/drugs/DB08837
    Investigational

    Because of its inhibitory actions at the autonomic ganglia, tetraethylammonium was thought to be a potential therapeutic vasodilator but serious toxic effects were found. … Tetraethylammonium is an experimental drug with no approved indication or marketed formulation.

  7. Drug

    Dexamethasone acetate

    go.drugbank.com/drugs/DB14649
    ApprovedInvestigationalVet approved

    [A188724] Dexamethasone acetate has largely been replaced by [dexamethasone] phosphate and continues to be administered for a large variety of inflammatory conditions. … [T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as [hydrocortisone] and [prednisolone].

  8. Drug

    Procaterol

    go.drugbank.com/drugs/DB01366
    ApprovedWithdrawn

    It is a potent bronchodilator that may be administered orally or by aerosol inhalation.

    Categories: Adrenergics for Systemic Use, Drugs for Obstructive Airway Diseases
  9. Drug

    Camostat

    go.drugbank.com/drugs/DB13729
    Investigational

    [A198807] Camostat mesylate inhibits cholecystokinin, pro-inflammatory cytokines, and serine proteases, leading to it being investigated for multiple indications including the treatment of COVID-19. … Camostat mesylate, or FOY-305, is a synthetic serine protease inhibitor.

  10. Drug

    Taurolidine

    go.drugbank.com/drugs/DB12473
    ApprovedInvestigational

    Taurolidine is an antimicrobial used for the prevention of catheter-related infections. It is a derivative of the amino acid [taurine]. … and Antifungal Drugs (LPAD pathway) for the prevention of catheter-related bloodstream infections in a limited and specific patient population.