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Displaying results 361 - 370 of 10000 in total
  1. Drug

    Eplerenone

    go.drugbank.com/drugs/DB00700
    ApprovedInvestigational

    Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: EPLERENON AL 25MG FTA, EPLERENON AL 50MG FTA
  2. Drug

    Desvenlafaxine

    go.drugbank.com/drugs/DB06700
    ApprovedInvestigational

    [A261271] Desvenlafaxine has a very similar pharmacological, efficacy, and safety profile as [venlafaxine]. … [L6016,A261271] MDD is a highly prevalent psychiatric disorder, with a lifetime prevalence estimate of 16% in the US alone and 12.8% in Europe.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: Ag-desvenlafaxine
  3. Drug

    Diphenhydramine

    go.drugbank.com/drugs/DB01075
    ApprovedInvestigational

    As a result, diphenhydramine is being investigated for its anxiolytic and anti-depressant properties. … Diphenhydramine - perhaps known most commonly as its brand name formulation Benadryl - is a first-generation H1 receptor antihistamine that is used extensively for the treatment of seasonal allergies,

    Mixtures: Au Kah Chuen Fugical, Bennatuss AF ExpectorantCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  4. Drug

    Lisdexamfetamine

    go.drugbank.com/drugs/DB01255
    ApprovedInvestigational

    Lisdexamfetamine is a prodrug of [dextroamphetamine], a central nervous system stimulant known as d-amphetamine,[A40246] covalently attached to the naturally occurring amino acid L-lysine.

    Products: Ag-lisdexamfetamine
  5. Drug

    Pantoprazole

    go.drugbank.com/drugs/DB00213
    ApprovedInvestigational

    [A177577, A177580] Pantoprazole doses should be slowly lowered, or tapered, before discontinuing as rapid discontinuation of PPIs such as pantoprazole may cause a rebound effect and a short term increase … [FDA Label] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.

    Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsProducts: Ag-pantoprazole, Ava-pantoprazole
  6. Drug

    Griseofulvin

    go.drugbank.com/drugs/DB00400
    ApprovedVet approved

    An antifungal antibiotic. Griseofulvin may be given by mouth in the treatment of tinea infections.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP3A InducersProducts: Grifulvin V, Fulvicin P/G 165
  7. Drug

    Magnesium

    go.drugbank.com/drugs/DB14513
    ApprovedInvestigational

    Magnesium is classified as an alkaline earth metal and has 2 hydration shells. … [A39559] Several factors and common behaviours reduce the availability of magnesium in the diet such as food processing and cooking vegetables (which are normally a rich source of magnesium).[A39559]

    Mixtures: T-PA Cap, Fusion PM Formula TabProducts: MAGNEROT A 500 BEUTEL, MAGNESIUM AL 243MG BTA
  8. Drug

    Famciclovir

    go.drugbank.com/drugs/DB00426
    ApprovedInvestigational

    Famciclovir, marketed as Famvir by Novartis, is a guanine analogue used to treat herpes virus infections. It is most commonly used to treat herpes zoster (shingles). … Famciclovir is a prodrug of penciclovir with higher oral bioavailability.

    Products: Ava-famciclovir
  9. Drug

    Captopril

    go.drugbank.com/drugs/DB01197
    ApprovedInvestigational

    ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension. … Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Mixtures: CAPTOPRIL HCT AL 50/25Categories: P-glycoprotein inhibitors
  10. Drug

    Albuterol

    go.drugbank.com/drugs/DB01001
    ApprovedInvestigationalVet approved

    Salbutamol is formulated as a racemic mixture of the R- and S-isomers. … Salbutamol (Albuterol [USAN]) is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Ventolin Nebules PF Sol 5mg/2.5ml, SALBUTAMOL AL INHALAT