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Ixekizumab
go.drugbank.com/drugs/DB11569ApprovedInvestigationalIxekizumab is produced by recombinant DNA technology in a recombinant mammalian cell line and purified using standard technology for bioprocessing. … As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions.
Products: Taltz 80mg solution for injection in pre-filled pen, TALTZ SOLUTION FOR INJECTION IN PRE-FILLED PEN 80 mg/mlIodipamide
go.drugbank.com/drugs/DB04711ApprovedWithdrawnIodipamide is a water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
Mixtures: Sinografin - Liq IuCategories: Compounds used in a research, industrial, or household settingBeta carotene
go.drugbank.com/drugs/DB06755ApprovedNutraceuticalIt is an antioxidant that can be found in yellow, orange and green leafy vegetables and fruits.[T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS). … [T162] It is the most abundant form of carotenoid and it is a precursor of the vitamin A. Beta-carotene is composed of two retinyl groups.
Mixtures: Vc II, Multipack IICategories: Vitamin APentoxifylline
go.drugbank.com/drugs/DB00806ApprovedInvestigational[A226415, L30300] Although originally developed to treat intermittent claudication, a form of exertion-induced leg pain common in patients with peripheral arterial disease, PTX has been investigated for … [A226608] Pentoxifylline has been marketed in Europe since 1972; PTX extended-release tablets sold under the trade name TRENTAL by US Pharm Holdings were first approved by the FDA on Aug 30, 1984, but
Categories: Compounds used in a research, industrial, or household settingInternational brands: Ao Le Ni, An Ruo NingMagaldrate
go.drugbank.com/drugs/DB08938ApprovedInvestigationalWithdrawnMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
Mixtures: M A L D I MProducts: MAGALDRATO SPECIAL PRODUCT'S LINEInclisiran
go.drugbank.com/drugs/DB14901ApprovedInvestigationalis a major known risk factor for CVD. … Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density
Categories: Compounds used in a research, industrial, or household settingProducts: LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 ML, Sybrava 284mg/1.5ml Solution for Injection in Pre-filled SyringeFluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalA pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2A6 Substrates with a Narrow Therapeutic IndexProducts: FLURO-5 DEVA 5000 MG/100 ML IV/IA ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 1 ADET, FLUOROURACİL-KOÇAK 250 MG/5 ML İV/İA İNFÜZYONLUK/ENJEKSİYONLUK ÇÖZELTİEphedra sinica root
go.drugbank.com/drugs/DB01363ApprovedNutraceuticalThe sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 due to the risk for adverse effects and a lack of evidence for … The drug is still sold in Canada in OTC formulations for respiratory conditions associated with bronchial asthma.
Mixtures: Dr. Miller's Formula No. 1Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesEsketamine
go.drugbank.com/drugs/DB11823ApprovedInvestigationalThe FDA approved ketamine (Ketalar) in 1970. … [L5593] Esketamine may prove to be a promising treatment for patients diagnosed with major depressive disorder who have not experienced an improvement in symptoms despite treatment with various medications
Categories: Non-Competitive N-Methyl D-Aspartate (NMDA) Receptor AntagonistsSynonyms: L-ketamineCalcitriol
go.drugbank.com/drugs/DB00136ApprovedInvestigationalNutraceuticalIt is produced in the body after series of conversion steps of 7-dehydrocholesterol from exposure to UV light. 7-dehydrocholesterol is converted to [DB00169] (vitamin D3) in the skin, which is then converted … Calcitriol is considered to be the most potent metabolite of vitamin D in humans [A3366]. Renal production of calcitriol is stimulated in response to PTH, low calcium and low phosphate [A26353].
Categories: Vitamin D and AnaloguesSynonyms: 1α,25-dihydroxyvitamin D3, 1-alpha-25-Dihydroxyvitamin D3