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Lapatinib
go.drugbank.com/drugs/DB01259ApprovedInvestigationalLapatinib is a human epidermal growth factor receptor type 2 (HER2/ERBB2) and epidermal growth factor receptor (HER1/EGFR/ERBB1) tyrosine kinases inhibitor. … Lapatinib is an anti-cancer drug developed by GlaxoSmithKline (GSK) as a treatment for solid tumours such as breast and lung cancer.
Synonyms: N-(3-chloro-4-((3-fluorophenyl)methoxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)-2-furanyl)-4-quinazolinamineCategories: Heterocyclic Compounds, 2-Ring, Human epidermal growth factor receptor 2 (HER2) tyrosine kinase inhibitorsTriptorelin
go.drugbank.com/drugs/DB06825ApprovedInvestigationalVet approvedTriptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH). … Serum testosterone concentrations may fall to levels typically observed in surgically castrated men.
Synonyms: (6-D-Tryptophan)luteinizing hormone-releasing hormone, (D-Trp6)-GnRHProducts: DECAPEPTYL 0,5 MG/ML ENJEKTABL SOLÜSYON, 7 ADET, GONAPEPTYL 0,1 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADETFenofibrate
go.drugbank.com/drugs/DB01039ApprovedInvestigational[L8588,L8591] Fenofibrate was granted FDA approval on 31 December 1993.[L8585] … Fenofibrate is a fibric acid derivative like [clofibrate] and [gemfibrozil].[A185954] Fenofibrate is used to treat primary hypercholesterolemia, mixed dyslipidemia, severe hypertriglyceridemia.
Synonyms: 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester, Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionateMixtures: SIMITRI® 145/40 MG, ACIDO FENOFIBRICO / ROSUVASTATINA 135 MG/10 MGBenazepril
go.drugbank.com/drugs/DB00542ApprovedInvestigationalBenazepril, brand name Lotensin, is a medication used to treat high blood pressure (hypertension), congestive heart failure, and chronic renal failure[A838,A837]. … Upon cleavage of its ester group by the liver, benazepril is converted into its active form benazeprilat, a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor[A836].
Mixtures: CİBADREX 5/6,25 MG FİLM TABLET, 28 ADET, CİBADREX 10/12,5 MG FİLM TABLET, 28 ADETCategories: Heterocyclic Compounds, 2-Ring, Agents Acting on the Renin-Angiotensin SystemTrimethobenzamide
go.drugbank.com/drugs/DB00662ApprovedInvestigationalTrimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). … In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Mixtures: EMEDUR 100 MG/20 MG SUPOZİTUAR, 5 ADET, EMEDUR 200 MG SUPOZITUAR, 5 ADETSynonyms: N-[[4-(2-dimethylaminoethoxy)phenyl]methyl]-3,4,5-trimethoxybenzamideLetrozole
go.drugbank.com/drugs/DB01006ApprovedInvestigational[A190546] Letrozole was granted FDA approval on 25 July 1997.[L11623] … Letrozole, or CGS 20267, is an oral non-steroidal type II aromatase inhibitor first described in the literature in 1990.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: LETROZOL SUN 2.5 MG, LETARA® 2.5 MG TABLETASThioridazine
go.drugbank.com/drugs/DB00679ApprovedWithdrawnA phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. … Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618).
Synonyms: 3-Methylmercapto-N-(2'-(N-methyl-2-piperidyl)ethyl)phenothiazine, 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazineInternational brands: Mellaril-SLevocetirizine
go.drugbank.com/drugs/DB06282ApprovedInvestigational[L7694] Levocetirizine has greater affinity for the histamine H<sub>1</sub> receptor than cetirizine.[L7694] Levocetirizine was granted FDA approval in 1995.[L7694] … Levocetirizine is a selective histamine H<sub>1</sub> antagonist used to treat a variety of allergic symptoms.[A181748,A181790,L7694] It is the R enantiomer of [cetirizine].
Synonyms: 2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acidMixtures: BROCRIPTIN® 10 MG/ 5 MG, LEPIXOS 5 MG/10 MG FILM TABLET ,30 ADETNitrofurantoin
go.drugbank.com/drugs/DB00698ApprovedInvestigationalVet approved[A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole].[A179830] Nitrofurantoin was granted FDA approval on 6 February 1953.[L6895] … [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.
Synonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoin, 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedioneCategories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingErdosteine
go.drugbank.com/drugs/DB05057ApprovedInvestigationalErdosteine is a drug that causes a breakdown of mucus, also known as a _mucolytic_ agent. … It is a _thiol_ derivative produced for the clinical management of chronic obstructive bronchitis, in addition to infective exacerbations of chronic bronchitis.
Categories: Heterocyclic Compounds, 1-RingProducts: ENZEVİN 175 MG/5 ML SUSPANSIYON ICIN KURU TOZ, 100 ML, ENZEVİN 175 MG/5 ML SUSPANSIYON ICIN KURU TOZ, 200 ML