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Esomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalAs the binding of esomeprazole to the (H+, K+)-ATPase enzyme is irreversible and new enzyme needs to be expressed in order to resume acid secretion, esomeprazole's duration of antisecretory effect persists
Sage oil
go.drugbank.com/drugs/DB11199ApprovedNutraceuticalThe main constituents of sage oil include camphor, 1,8-cineole, α-thujone, β-thujone, borneol, and viridiflorol, which are thought to mainly produce the biological effects of sage oil. … Sage oil is extracted from sage or *Salvia officinalis*, the herb commonly used for culinary purposes.
Synonyms: Sage oil, Common sage oilCedar oil
go.drugbank.com/drugs/DB10917ApprovedCedar oil (Juniperus virginiana) allergenic extract is used in allergenic testing.
Synonyms: Cedar oil, Cedarwood oilHomosalate
go.drugbank.com/drugs/DB11064ApprovedHomosalate is an organic compound that belongs to salicylates. It is an ester formed from salicylic acid and 3,3,5-trimethylcyclohexanol, a derivative of cyclohexanol. Salicylates prevent direct skin exposure to the sun’s harmful rays by...
Mixtures: Aloe Up Lil Kids SPF 50, Aloe Up Light Tanning Oil SPF-6Pravastatin
go.drugbank.com/drugs/DB00175ApprovedInvestigationalPravastatin is the 6-alpha-hydroxy acid form of mevastatin. Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug....
Olokizumab
go.drugbank.com/drugs/DB13127InvestigationalTargeting IL-6 function can be achieved directly, or through interrupting the IL-6 receptor or gp130 receptor axes. … [A241185, A241175] Olokizumab is a humanized anti-IL-6 IgG4κ antibody that directly blocks gp130 binding at IL-6 Site 3.[A241045]
Acute Ulcerative Colitis
go.drugbank.com/conditions/DBCOND0065067Drugs: MesalazineSynonyms: Colitis gravis, Colitis gravis, NOSDelgocitinib
go.drugbank.com/drugs/DB16133ApprovedInvestigationalDelgocitinib is a pan-Janus kinase (JAK) inhibitor. After the first global approval in Japan, delgocitinib was also approved by the European Commission on September 23, 2024. It works to reduce the inflammatory response in inflammatory s...
Entecavir
go.drugbank.com/drugs/DB00442ApprovedInvestigationalEntecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine
Human interleukin-2
go.drugbank.com/drugs/DB14865InvestigationalHuman interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).
Synonyms: IL 2, IL-2