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Cyclosporine
go.drugbank.com/drugs/DB00091ApprovedInvestigationalVet approvedIt is isolated from the fungus _Beauveria nivea_. … [A174049] Initially manufactured by Sandoz and approved for use by the FDA in 1983, cyclosporine is now available in various products by Novartis (previously known as Sandoz).[L11097,L3734,L11118]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: CYLORİN 100 MG YUMUŞAK KAPSÜL, 50 ADET, LYMUNİR 100 MG YUMUŞAK KAPSÜL, 50 ADETGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … [L33110] It is one of the most commonly prescribed anticholinergic medications.
Mixtures: ENERZAIR BREEZHALER INHALATION POWDER, HARD CAPSULE 150 MCG /50 MCG /160 MCG, ULTIBRO BREEZHALER INHALATION POWDER HARD CAPSULE 110/50 MCGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesLipoic acid
go.drugbank.com/drugs/DB00166ApprovedInvestigationalNutraceuticalA vitamin-like antioxidant.
Mixtures: BENEDAY 250/250/1/300 MG 50 ENTERIK KAPLI TABLET, CHALİA 250/250/1/300 MG GASTRO-REZİSTAN TABLET, 50 ADETCategories: Compounds used in a research, industrial, or household settingCeftibuten
go.drugbank.com/drugs/DB01415ApprovedInvestigationalIt is typically used to treat acute bacterial exacerbations of chronic bronchitis (ABECB), acute bacterial otitis media, pharyngitis, and tonsilitis.
Mixtures: BUCEF PLUS 180/62.5 MG TOZ ICEREN SASE, 20 ADET, WINCEF PLUS 180/62.5 MG/5 ML ORAL SUSPANSIYON HAZIRLAMAK ICIN KURU TOZ, 100 MLCategories: Heterocyclic Compounds, 2-RingRifaximin
go.drugbank.com/drugs/DB01220ApprovedInvestigationalIt has multiple indications and is used in treatment of traveller's diarrhea caused by E. coli; reduction in risk of overt hepatic encephalopathy recurrence; as well as diarrhea-predominant irritable bowel … syndrome (IBS-D) in adult women and men.
Synonyms: Rifamycin L 105Categories: Heterocyclic Compounds with 4 or More Rings, Cytochrome P-450 SubstratesEphedrine
go.drugbank.com/drugs/DB01364ApprovedInvestigational[A193701,A193704,L12975] Ephedrine was granted a type 7 FDA Approval on 29 April 2016.[L12975] … It is an alpha- and beta-adrenergic receptor agonist; however, it also causes the indirect release of norepinephrine from sympathetic neurons, inhibiting norepinephrine reuptake and displacing more norepinephrine
Mixtures: BROKSIN 6.66 MG/5 ML+100 MG/5 ML SURUP, 150 ML, COPHADYL-E COUGH LINCTUSCategories: Herbs and Natural ProductsNimesulide
go.drugbank.com/drugs/DB04743ApprovedWithdrawnNimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. … Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries.
Mixtures: ETNA COMBO 100 MG/8 MG TABLET, 14 ADET, NİMES COMBO 100 MG / 8 MG TABLET , 14 ADETCategories: Selective Cyclooxygenase 2 Inhibitors (NSAIDs), Cytochrome P-450 SubstratesCarboplatin
go.drugbank.com/drugs/DB00958ApprovedInvestigationalCarboplatin is an organoplatinum antineoplastic alkylating agent used in the treatment of advanced ovarian carcinoma.[L32253] Early clinical studies of carboplatin were performed in 1982. … [A230523] Carboplatin was developed as an analog of [cisplatin] with reduced nephrotoxicity and vomiting.[A230463,A230523] Carboplatin was granted FDA approval on 3 March 1989.[L32248]
Synonyms: Platinum, diammine [1,1-cyclobutane-dicarboxylato(2-)-0,0']-,(SP-4-2)Categories: Compounds used in a research, industrial, or household settingMirabegron
go.drugbank.com/drugs/DB08893ApprovedInvestigational[L32853] Mirabegron is also used in other jurisdictions across the globe, including Canada,[L32925] the EU,[L32945] and Japan.[A7469] … It is unique amongst overactive bladder treatment options in that, unlike other treatments such as [solifenacin] and [darifenacin], it lacks significant antimuscarinic activity,[A232553] which is responsible
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: BETMIGA 25 MG UZATILMIŞ SALIMLI FILM TABLET , 10 TABLET, BETMIGA 50 MG UZATILMIŞ SALIMLI FILM TABLET ,100 TABLETZidovudine
go.drugbank.com/drugs/DB00495ApprovedInvestigationalA dideoxynucleoside compound in which the 3'-hydroxy group on the sugar moiety has been replaced by an azido group. … It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS.
Mixtures: COMBİVİR 150 MG/300 MG FİLM KAPLI TABLET, LAMIVUDINA 150 MG & ZIDOVUDINA 300 MG TABLETASCategories: Antivirals used in combination for the treatment of HIV infections, Cytochrome P-450 Substrates