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Ebvaciclib
go.drugbank.com/drugs/DB18967InvestigationalEbvaciclib is under investigation in clinical trial NCT03519178 (A Study of PF-06873600 in People With Cancer).
Mosliciguat
go.drugbank.com/drugs/DB19425InvestigationalMosliciguat is under investigation in clinical trial NCT06635850 (A Phase 2 Study of Mosliciguat in PH-ILD).
Raltegravir
go.drugbank.com/drugs/DB06817ApprovedInvestigationalRaltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseSaruparib
go.drugbank.com/drugs/DB18982InvestigationalSaruparib is under investigation in clinical trial NCT06380751 (Saruparib (AZD5305) Plus Camizestrant Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in Hr-positive, Her2-negative
Parathyroid hormone
go.drugbank.com/drugs/DB05829ApprovedInvestigationalAvailable as Preotact, it is an identical form of human recombinant hormome which produced as a fusion protein undergoeing post-translational processing involving the cleavage of the OmpA leader sequence
Veglin
go.drugbank.com/drugs/DB05890ExperimentalVEGF-AS (Veglin) is an anti-angiogenesis non-chemotherapy drug (angiogenesis inhibitor) that was developed by VasGene Therapeutics, Inc. for the treatment of a variety of malignancies including mesothelioma … Veglin is one of several newly developed non-chemotherapy drugs being tested for possible utilization in the ongoing struggle to combat malignant mesothelioma.
Acitretin
go.drugbank.com/drugs/DB00459ApprovedInvestigationalAn oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Categories: Antipsoriatics for Systemic Use, Retinoids for Treatment of PsoriasisTreprostinil
go.drugbank.com/drugs/DB00374ApprovedInvestigationalHowever, the use of epoprostenol is limited due to its short half-life (3-5 min) and instability at room temperature. … Treprostinil was approved by the FDA in 2002 for the treatment of pulmonary arterial hypertension.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesDeoxycholic acid
go.drugbank.com/drugs/DB03619ApprovedInvestigationalIt is marketed under the brand name Kybella by Kythera Biopharma and is the first pharmacological agent available for submental fat reduction, allowing for a safer and less invasive alternative than surgical … In April 2015, deoxycholic acid was approved by the FDA for the treatment submental fat to improve aesthetic appearance and reduce facial fullness or convexity.