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Displaying results 3701 - 3710 of 10000 in total
  1. Drug

    Metyrapone

    go.drugbank.com/drugs/DB01011
    ApprovedInvestigational

    An inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.

    Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2A6 InhibitorsProducts: Metycor 250 mg Weichkapseln
  2. Drug

    Reboxetine

    go.drugbank.com/drugs/DB00234
    ApprovedInvestigationalWithdrawn

    Reboxetine has two chiral centers, but it only exists as two enantiomers, (R,R)-(-)- and (S,S)-(+)-reboxetine.

    Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: EDRONAX 4 MG TABLET, 60 ADET, Edronax 4 mg - Tabletten
  3. Drug

    Arformoterol

    go.drugbank.com/drugs/DB01274
    Approved

    Arformoterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.

    Mixtures: AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 120 KPS, AIRBIR 3/100 MCG INHALASYON IÇIN TOZ IÇEREN KAPSÜL, 60 KPSCategories: Cytochrome P-450 Substrates, Adrenergic beta-2 Receptor Agonists
  4. Drug

    DL-alpha tocopheryl acetate

    go.drugbank.com/drugs/DB14477
    Approved

    Mixtures: Folika-MG, Davimet-MCategories: Vitamin E
  5. Drug

    Teriparatide

    go.drugbank.com/drugs/DB06285
    ApprovedInvestigational

    Teriparatide is a recombinant parathyroid hormone (PTH) analog and a potent osteoanabolic agent.[A251395] It is made up of the first amino(N)-terminal 34 amino acids of the human PTH. … [A251395] First approved in the United States in November 2002 and in Europe in April 2003,[A251400] teriparatide makes the first approved drug in a new category of osteoporosis therapy called anabolic

    Synonyms: PTH 1-34, PTH (1-34)Products: FORTEO® 250MCG/ML, MEGAPTH-G Teriparatide 20 micrograms / 80 microliters solution for injection
  6. Drug

    Calcium ascorbate

    go.drugbank.com/drugs/DB14483
    ApprovedNutraceutical

    Mixtures: Supplements De Vitamines Et Mineraux, Ester-C 500 mgCategories: Vitamin C and analogues, Compounds used in a research, industrial, or household setting
  7. Drug

    Luspatercept

    go.drugbank.com/drugs/DB12281
    ApprovedInvestigational

    [A187829,L42455] It was first approved for use in the United States in November 2019 under the brand name Reblozyl® for the treatment of anemia in patients with beta thalassemia who require regular blood … Luspatercept is a recombinant fusion protein comprised of a modified extracellular domain of activin receptor type IIB fused to the FC domain of human IgG1.

    Products: Reblozyl 25 mg powder for solution for injection, Reblozyl 75 mg powder for solution for injection
  8. Drug

    Serrapeptase

    go.drugbank.com/drugs/DB13131
    Investigational

    Serratiopeptidase is under investigation in clinical trial NCT02493179 (Efficacy Evaluation of the (Serodase 5 mg Tablet) in the Treatment of Inflammation After Third Molar Surgery). … Serrapeptase is a proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections.

    Products: แซนแดน-5, เซอราสตาร์-5
  9. Target

    Solute carrier family 12 member 5

    go.drugbank.com/bio_entities/BE0000047
    TargetTransporterHumans

    Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis (PubMed:12106695). As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required...

    Polypeptides: Solute carrier family 12 member 5
  10. Target

    cGMP-specific 3',5'-cyclic phosphodiesterase

    go.drugbank.com/bio_entities/BE0000182
    TargetEnzymeHumans

    This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP (PubMed:15489334, PubMed:9714779). Specifically regulates nitric-oxide-generated cGMP (PubMed:15489334)

    Polypeptides: cGMP-specific 3',5'-cyclic phosphodiesteraseFunction: 3',5'-cyclic-AMP phosphodiesterase activity