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TrenibotulinumtoxinE
go.drugbank.com/drugs/DB19082Approved[L64095,L64118] It is given as an intramuscular injection into the corrugator and procerus muscles, is intended for occasional use, and its potency units are not interchangeable with those of other botulinum
ATN-161
go.drugbank.com/drugs/DB05491InvestigationalThis approach targeting both the tumor vasculature and the cancer cells themselves, may be effective in single therapy as well as combination therapy.
NasoVAX
go.drugbank.com/drugs/DB15859InvestigationalCreated by Altimmune, Inc., NasoVAX is currently being developed for seasonal and pandemic use as it can activate humoral and cellular immune responses. … As of June 2020, NasoVAX is being evaluated in a Phase 2 clinical trial for safety and effectivness in preventing worsening symptoms in hospitalized COVID-19 patients (NCT04442230).
Niflumic acid
go.drugbank.com/drugs/DB04552InvestigationalNiflumic acid is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis.
GFT14
go.drugbank.com/drugs/DB05061ExperimentalGFT14 aims to target mixed dyslipidemia of type IIb (high levels of triglycerides and LDL-C) as one of the major indications of cardiometabolic disease. … condition of patients at risk from cardiovascular disease by a simultaneous and favorable action on the plasmatic lipids (rise of HDL- cholesterol et lowering of triglycerides) and on other risk factors such as
Allogenic Human Umbilical Derived Mesenchymal Stem Cells in Conditioned Media
go.drugbank.com/drugs/DB15728ExperimentalOne of these companies, Aspire, has created their own product, ACT-20 Conditioned Medium as a product for testing. … In comparison to bone-marrow derived MSCs, these cells are more resilient, easier to extract, and generally regarded as less immunogenic.
Spermidine
go.drugbank.com/drugs/DB03566InvestigationalIt is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
Epitestosterone
go.drugbank.com/drugs/DB07768ExperimentalEpitestosterone acts as an antiandrogen in various target tissues. The ratio between testosterone/epitestosterone is used to monitor anabolic drug abuse.
Cabamiquine
go.drugbank.com/drugs/DB21477InvestigationalCabamiquine is under investigation in clinical trial NCT05974267 (Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium
AstraZeneca COVID-19 Vaccine
go.drugbank.com/drugs/DB15656ApprovedInvestigationalThe AstraZeneca COVID-19 Vaccine (previously known as ChAdOx1 nCoV-19 or AZD1222) is one of several vaccines developed in 2020 for the prevention of COVID-19 caused by SARS-CoV-2. … [L12669,L32649] The ChAdOx1 viral vector was developed at the University of Oxford and has been investigated as a potential vector for vaccines against another human coronavirus, Middle Eastern respiratory