Niflumic acid

DB04552InvestigationalSmall molecule

Niflumic acid is a cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.

Chemical structure of Niflumic acid
Mechanism
Curator reviewed
Primary indication
Used in the treatment of rheumatoid arthritis.Curator reviewed · 17 structured indications
Formula / weight
C13H9F3N2O2 · 282.218 g/mol (avg)
Code names
Lopac-N-0630 · UP-83

Resolves to

Compound
UNII4U5MP5IUD8CAS4394-00-7ChEMBLCHEMBL63323ChEBI34888PubChem4488KEGGD08275
Clinical / RWD
RxNorm7418ATCM01AX02ATCM02AA17PharmGKBPA164746749
Structure
InChIKeyJZFPYUNJRRFVQU-UHFFFAOYSA-NSMILESOC(=O)C1=C(NC2=CC=CC(=C2)C(F)(F)F)N=CC=C1
Targets
P04054PLA2G1BP35354PTGS2P51800CLCNKAP23219PTGS1P47712PLA2G4AO60656UGT1A9
Transporters
O60669SLC16A7P53985SLC16A1

What you can answer from here — as of February 24, 2026

6Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
2TransportersSubstrate / inhibitor direction, not just membership
Listed above
1,437Drug interactionsStructured to mechanism, not free text
Sign in
1Clinical trialPhase, status and sponsor resolved per trial
Sign in
17Structured indicationsCondition, population, route and combination as fields, not prose
Sign in
11ContraindicationsEach with its own population and attribute set
Sign in
6Marketed productsAcross 1 country and 4 labellers
Sign in
2ATC codesIncluding every combination product, plus 28 drug categories
Sign in
17+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with Niflumic acid, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In