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Displaying results 3721 - 3730 of 5897 in total
  1. Drug

    Encorafenib

    go.drugbank.com/drugs/DB11718
    ApprovedInvestigational

    Encorafenib, also known as BRAFTOVI, is a kinase inhibitor. Encorafenib inhibits BRAF gene, which encodes for B-raf protein, which is a proto-oncogene involved in various genetic mutations. This protein plays a role in regulating the MAP...

  2. Drug

    Tegoprazan

    go.drugbank.com/drugs/DB16690
    Investigational

    [A234215, A234220] Tegoprazan’s strong and sustained effect is due to its ability to be slowly cleared from the gastric glands and exertion of effects independent of acid levels. … [A234220] It has also been observed to be efficacious independent of food intake.[A234220]

  3. Drug

    Methylmalonic Acid

    go.drugbank.com/drugs/DB04183
    Experimental

    Abnormalities in methylmalonic acid metabolism lead to methylmalonic aciduria. This metabolic disease is attributed to a block in the enzymatic conversion of methylmalonyl CoA to succinyl CoA.

  4. Drug

    AVI-7537

    go.drugbank.com/drugs/DB15433
    Investigational

    AVI-7537 is an antisense molecule that binds to the Ebola virus mRNA to prevent the viral replication. … [L46207] AVI-7537 is under investigation in clinical trial NCT01593072 (A Study to Assess the Safety, Tolerability and Pharmacokinetics of AVI-7537 in Healthy Adult Volunteers).

  5. Drug

    PRO 2000

    go.drugbank.com/drugs/DB05385
    Investigational

    This medicine does not cure HIV infection or AIDS and is being studied to reduce the risk of passing the virus to other people.

  6. Drug

    Malacidin A

    go.drugbank.com/drugs/DB14051
    Experimental

    While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears to act via its own distinct mechanism.

  7. Drug

    Malacidin B

    go.drugbank.com/drugs/DB14052
    Experimental

    While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin B appears to act via its own distinct mechanism.

  8. Drug

    Faropenem medoxomil

    go.drugbank.com/drugs/DB05659
    Investigational

    The prodrug form of faropenem offers dramatically improved oral bioavailability and leads to higher systemic concentrations of the drug. … Faropenem medoxomil is a broad-spectrum antibiotic that is highly resistant to beta-lactamase degradation. It is being developed jointly by Replidyne, Inc. and Forest Laboratories, Inc.

  9. Drug

    Nordazepam

    go.drugbank.com/drugs/DB14028
    Investigational

    An intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.

  10. Drug

    Motexafin gadolinium

    go.drugbank.com/drugs/DB05428
    Investigational

    It belongs to the family of drugs called metalloporphyrin complexes. Also called gadolinium texaphyrin. … It may make tumor cells more sensitive to radiation therapy, improve tumor images using magnetic resonance imaging (MRI), and kill cancer cells.