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Displaying results 3741 - 3750 of 10000 in total
  1. Drug

    Tesetaxel

    go.drugbank.com/drugs/DB12019
    Investigational

    Tesetaxel has been used in trials studying the treatment of Cancer, Melanoma, Prostate Cancer, Gastric Carcinoma, and Advanced Melanoma, among others.

  2. Drug

    Sepetaprost

    go.drugbank.com/drugs/DB12043
    Investigational

    Sepetaprost has been used in trials studying the treatment of Open Angle-glaucoma, Ocular Hypertension, and Mild Open Angle-glaucoma (OAG).

    Categories: Heterocyclic Compounds, 1-Ring
  3. Drug

    BMS-599626

    go.drugbank.com/drugs/DB12318
    Investigational

    BMS-599626 has been used in trials studying the treatment of Cancer, Metastases, and HER2 or EGFR Expressing Advanced Solid Malignancies.

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Blisibimod

    go.drugbank.com/drugs/DB12330
    Investigational

    Blisibimod has been used in trials studying the treatment of IgA Nephropathy, Microscopic Polyangiitis, Systemic Lupus Erythematosus, and Granulomatosis With Polyangiitis.

    Categories: B-Cell Activating Factor
  5. Drug

    CPG-52852

    go.drugbank.com/drugs/DB12476
    Investigational

    852A has been used in trials studying the treatment of Melanoma, Neoplasms, Breast Cancer, Ovarian Cancer, and Cervical Cancer, among others.

    Synonyms: N-[4-(4-amino-2-ethylimidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide
  6. Drug

    TNP-470

    go.drugbank.com/drugs/DB08633
    Investigational

    O-(chloroacetylcarbamoyl)fumagillol (TNP-470) has been used in trials studying the treatment of HIV Infections, Sarcoma, Kaposi, and Pancreatic Neoplasms.

    Synonyms: O-(chloroacetylcarbamoyl)fumagillol, O-chloroacetylcarbamoylfumagillol
  7. Drug

    Rigosertib

    go.drugbank.com/drugs/DB12146
    Investigational

    Rigosertib has been used in trials studying the treatment and basic science of MDS, RAEB, Cancer, Hepatoma, and Neoplasms, among others.

  8. Target

    L-lactate dehydrogenase A chain

    go.drugbank.com/bio_entities/BE0000425
    TargetHumans

    Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)

    Synonyms: Cell proliferation-inducing gene 19 protein
  9. Target

    Transcription factor p65

    go.drugbank.com/bio_entities/BE0005551
    TargetHumans

    Besides its activity as a direct transcriptional activator, it is also able to modulate promoters accessibility to transcription factors and thereby indirectly regulate gene expression. … Essential for cytokine gene expression in T-cells (PubMed:15790681). The NF-kappa-B homodimeric RELA-RELA complex appears to be involved in invasin-mediated activation of IL-8 expression.

    Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
  10. Target

    Ubiquitin-conjugating enzyme E2 T

    go.drugbank.com/bio_entities/BE0019778
    TargetHumans

    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair. Acts as a specific E2 ubiquitin-conjugating enzyme for the Fan...

    Synonyms: Cell proliferation-inducing gene 50 protein