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PIK-75
go.drugbank.com/drugs/DB17047ExperimentalPIK-75 is a preferential p110 alpha/gamma PI3K inhibitor.[A253097]
Synonyms: Benzenesulfonic acid, 2-methyl-5-nitro-, 2-((6-bromoimidazo(1,2-a)pyridin-3-yl)methylene)-1-methylhydrazidePlumbagin
go.drugbank.com/drugs/DB17048InvestigationalPlumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]
Categories: Compounds used in a research, industrial, or household settingRS-39604
go.drugbank.com/drugs/DB17050ExperimentalRS-39604 is a selective 5-HT4 receptor antagonist.[A253112]
SB-218078
go.drugbank.com/drugs/DB17051ExperimentalSB-218078 is a specific inhibitor of CHK1.[A253117]
Scriptaid
go.drugbank.com/drugs/DB17053ExperimentalScriptaid is a histone deacetylase (HDAC) inhibitor researched for its anti-tumor properties.[A253127]
SKF-96365 free base
go.drugbank.com/drugs/DB17054ExperimentalSKF-96365 is a receptor-mediated calcium entry (RMCE) inhibitor structurally different from other calcium antagonists.[A253132]
SNX-2112
go.drugbank.com/drugs/DB17055ExperimentalSNX-2112 is a heat shock protein 90 (Hsp90) inhibitor.[A253137]
JZP-386 free base
go.drugbank.com/drugs/DB17068ExperimentalJZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.
LY3884961
go.drugbank.com/drugs/DB17070InvestigationalLY3884961 (previously PR001) is being developed by Prevail Therapeutics as a single-dose gene therapy for patients with Parkinson's disease and Gaucher disease.[L43468]
MYR-101
go.drugbank.com/drugs/DB17075InvestigationalIt is caused by a mutation in the aspartoacylase gene (_ASPA_), which leads to a deficiency of the aspartoacylase enzyme (ASPA). … Canavan disease is a fatal childhood genetic disorder characterized by white matter degeneration in the brain.