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Benzoylecgonine
go.drugbank.com/drugs/DB01515ExperimentalIllicitIt is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. … It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for the relief of muscle pain that is not FDA approved or on the market in the United States.
Oxabolone cipionate
go.drugbank.com/drugs/DB13185ExperimentalA synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone). It is considered as a performance enhancing drug thus is prohibited from use in sports.
Trefentanil
go.drugbank.com/drugs/DB09181ExperimentalIt is more potent and shorter acting than alfentanil. Trefentanil is not used in clinics due to the severity of its respiratory depression, though it is still used in research.
Dimenoxadol
go.drugbank.com/drugs/DB01461ExperimentalIllicitIt is structurally similar to methadone and is a benzilic acid derivative. In the United States it is classified as a Schedule I controlled drug.
Latrunculin A
go.drugbank.com/drugs/DB02621InvestigationalIt is under investigation for the treatment of cancer. It disrupts actin polymerization, prevents mitotic spindle formation and thus cell replication.
Azelastine
go.drugbank.com/drugs/DB00972ApprovedInvestigational[L8240,L8270] It is a racemic mixture, though there is no noted difference in pharmacologic activity between enantiomers, and was first granted FDA approval in 1996.
Products: AZEP NASAL SPRAY 1 mg/ml, Azedil 1 mg/ml NasensprayTunicamycin
go.drugbank.com/drugs/DB13172ExperimentalTunicamycin blocks N-linked glycosylation (N-glycans) resulting in cell cycle arrest at the G1 phase in human cells. It is used as an experimental tool to induce unfolded protein response.
Streptococcus pneumoniae type 22F capsular polysaccharide diphtheria CRM197 protein conjugate antigen
go.drugbank.com/drugs/DB16710ApprovedInvestigationalIt is contained in the vaccine under the market name Prevnar that contains the saccharides for serotypes 4, 6B, 9V, 14, 18C, 19F, and 23F for intramuscular injection.
KT-333
go.drugbank.com/drugs/DB17165InvestigationalKT-333 is a small molecule targeted protein degrader of STAT3.[L44086]