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Nitrofural
go.drugbank.com/drugs/DB00336ApprovedVet approvedWithdrawnNitrofural has also been administered orally in the treatment of trypanosomiasis. … Nitrofural or nitrofurazone is a topical anti-infective agent effective against gram-negative and gram-positive bacteria. It is used for superficial wounds, burns, ulcers, and skin infections.
Pinacidil
go.drugbank.com/drugs/DB06762ApprovedThe above processes result in reduced blood pressure. This drug has been discontinued by the FDA. … Pinacidil is a cyanoguanidine drug that acts by opening ATP-sensitive potassium channels, leading to peripheral vasodilatation of arterioles and decreasing peripheral vascular resistance.
Categories: Arteriolar Smooth Muscle, Agents Acting OnRotenone
go.drugbank.com/drugs/DB11457ExperimentalVet approvedRotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish.
Categories: Compounds used in a research, industrial, or household settingDodecyldimethylamine N-oxide
go.drugbank.com/drugs/DB04147ExperimentalSynonyms: N,N-Dimethyldodecylamine oxide, Dimethyldodecylamine N-oxideCategories: Compounds used in a research, industrial, or household settingMorrhuic acid
go.drugbank.com/drugs/DB14087InvestigationalMorrhuic acid is a mixture of unsaturated fatty acids obtained from cod liver oil.
Categories: Compounds used in a research, industrial, or household settingS-8510
go.drugbank.com/drugs/DB06504ExperimentalS-8510 / SB-737552 is a BZD inverse agonist investigated for the treatment of Alzheimer’s disease and mild to moderate senile dementia. It was being codeveloped by Shionogi and GlaxoSmithKline.
Ciluprevir
go.drugbank.com/drugs/DB05868InvestigationalThe compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.
Guanidine
go.drugbank.com/drugs/DB00536ApprovedIt is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. … (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.
Piclidenoson
go.drugbank.com/drugs/DB05511InvestigationalCF101 is supplied as an oral drug and has an excellent safety profile. … CF 101 (known generically as IB-MECA) is an anti-inflammatory drug for rheumatoid arthritis patients. Its novel mechanism of action relies on antagonism of adenoside A3 receptors.
Metiamide
go.drugbank.com/drugs/DB08805ExperimentalMetiamide is an H-2 receptor antagonist derived from burimamide. It was an intermediate product on the path to developing cimetidine.