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Displaying results 371 - 380 of 4433 in total
  1. Drug

    Entecavir

    go.drugbank.com/drugs/DB00442
    ApprovedInvestigational

    It was approved by the U.S. Food and Drug Administration (FDA) in March 2005.

    Products: BARACLUDE 1MG, ENTECAVIR AL 1MG
  2. Drug

    Olaparib

    go.drugbank.com/drugs/DB09074
    ApprovedInvestigational

    [L41100, L40908, L43792] It was first approved by the FDA and EU in December 2014,[A246020] and by Health Canada in April 2016.[L42820] … [L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell

    Products: LYNPARZA HARD CAPSULES 50MG, Lynparza 50mg Hard Capsules
  3. Drug

    Methotrimeprazine

    go.drugbank.com/drugs/DB01403
    Approved

    A phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlo...

    Products: LEVOMEPROMAZIN-NEURAX 10MG, Nov Meprazine Tab 50mg
  4. Drug

    Prasugrel

    go.drugbank.com/drugs/DB06209
    ApprovedInvestigational

    Prasugrel was developed by Daiichi Sankyo Co. and is currently marketed in the United States and Canada in cooperation with Eli Lilly and Company for acute coronary syndromes planned for percutaneous coronary

    Products: EFIENT 10MG, EFIENT 10MG FTA
  5. Drug

    Cefixime

    go.drugbank.com/drugs/DB00671
    ApprovedInvestigational

    [L49293] The beta-lactam ring of cefixime inhibits bacterial cell wall synthesis by binding to the penicillin-binding proteins which will then result in lysis.

    Products: CEFIXIMA MK 20MG/ML, hovid-Xyfisim Granules 50mg
  6. Drug

    Rifampin

    go.drugbank.com/drugs/DB01045
    ApprovedInvestigational

    [A263768] Rifampin is used to treat tuberculosis and works by inhibiting the microbial DNA-dependent RNA polymerase (RNAP).[A263768]

    Mixtures: RIFAMPICINA 300MG+ISONIAZIDA 150MGProducts: Rifadin Cap 300mg, Royce Rifampicin Capsule 300mg
  7. Drug

    Posaconazole

    go.drugbank.com/drugs/DB01263
    ApprovedInvestigationalVet approved

    Posaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.

    Products: Posaconazol Sandoz 40mg/ml - Suspension zum Einnehmen, NOXAFIL TABLET 100MG
  8. Drug

    Docetaxel

    go.drugbank.com/drugs/DB01248
    ApprovedInvestigational

    Docetaxel binds to microtubules but does not interact with dimeric tubulin. … [L46466] Docetaxel was approved by the FDA in 1996 and is available in solution for injection for intravenous or parenteral administration.[A259676]

    Products: Daxotel Injection Concentrate 40mg/ml, Docel Docetaxel Injection 10mg/mL
  9. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … By inhibiting the influx of calcium in smooth muscle cells, felodipine prevents calcium-dependent myocyte contraction and vasoconstriction.

    Products: FELOCOR 10MG, Renedil Srt 10mg
  10. Drug

    Irinotecan

    go.drugbank.com/drugs/DB00762
    ApprovedInvestigational

    [A263376] Approved by the FDA in 1996,[A263366] irinotecan is used to treat colorectal cancer and pancreatic adenocarcinoma. … Both irinotecan and SN-38 mediate antitumor activity by forming a complex with topoisomerase I and blocking its enzymatic activity, thereby interfering with DNA synthesis.

    Products: CAMPTO 40MG/2ML INJECTION, ONCOTAN INYECTABLE 40MG/2ML