Search

Displaying results 371 - 380 of 10000 in total
  1. Drug

    2'-Deoxycytidine 5'-triphosphate

    go.drugbank.com/drugs/DB03258
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 2'-Deoxycytidine 5'-triphosphate, 2'-Deoxycytidine-5'-Triphosphate
  2. Drug

    6-oxouridine 5'-phosphate

    go.drugbank.com/drugs/DB03668
    Experimental

    Synonyms: 6-oxouridine 5'-phosphate, 5,6-dihydro-6-oxouridine 5'-phosphate
  3. Drug

    TVI-Brain-1

    go.drugbank.com/drugs/DB17227
    Investigational

    Synonyms: Attenuated autologous cancer cells and granulocyte macrophage colony stimulating factor in combination with activated autologous blood derived T-cells, TVI-Brain-1
  4. Drug

    Exebacase

    go.drugbank.com/drugs/DB16161
    Investigational

    Exebacase is under investigation in clinical trial NCT03163446 (Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia).

    Synonyms: Des-met1-putative phage lysin (streptococcus phage phi891591), produced in escherichia coli
  5. Drug

    Almotriptan

    go.drugbank.com/drugs/DB00918
    Approved

    Almotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. … It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms

    Categories: Serotonin 5-HT1 Receptor Agonists, Selective Serotonin 5-HT1 Receptor AgonistsSynonyms: 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidine
  6. Drug

    Domperidone

    go.drugbank.com/drugs/DB01184
    ApprovedInvestigationalVet approved

    A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.

    Mixtures: LACOMBI 15/10 MG KAPSUL, 28 ADET, DUOLANS 15/30 MG SR KAPSUL, 28 ADETCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  7. Drug

    Oseltamivir

    go.drugbank.com/drugs/DB00198
    ApprovedInvestigational

    generally no benefit in use beyond 48 hours for healthy, low-risk individuals as influenza is a self-limiting illness. … They recommend the use of oseltamivir in people with a higher risk of developing complications including children younger than 2 years, people over 65 years, people with some chronic conditions or immunosuppression

    Synonyms: Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate, 1-Cyclohexene-1-carboxylic acid, 4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-, ethyl ester, (3R-(3alpha,4beta,5alpha))-Products: FLUHALT FOR ORAL SUSPENSION 60 mg/ 5 ml, STARFLU-75 CAPSULES 75 MG
  8. Drug

    Cobicistat

    go.drugbank.com/drugs/DB09065
    ApprovedInvestigational

    More specifically, cobicistat is indicated to increase systemic exposure of atazanavir or darunavir (once daily dosing regimen) in combination with other antiretroviral agents in the treatment of HIV-1 … Although it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered

    Mixtures: GENVOYA FILM COATED TABLET 150 MG/150 MG/200 MG/10 MG, STRIBILD FILM COATED TABLET 150 MG/150 MG/200 MG/245 MGCategories: Antivirals used in combination for the treatment of HIV infections, P-glycoprotein inhibitors
  9. Drug

    Rosuvastatin

    go.drugbank.com/drugs/DB01098
    ApprovedInvestigational

    [A181087, A181406] Evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within 5 years) statins cause a 20%-22% relative reduction in major cardiovascular … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid and is

    Mixtures: LODITEN 5/5 MG EFERVESAN TABLET, 30 ADET, LODITEN 5/5 MG EFERVESAN TABLET, 90 ADETCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates
  10. Drug

    Acoltremon

    go.drugbank.com/drugs/DB19202
    ApprovedInvestigational

    Acoltremon is under investigation in clinical trial NCT05493111 (A Long-term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512).

    Synonyms: Cyclohexanecarboxamide, n-(4-methoxyphenyl)-5-methyl-2-(1-methylethyl)-, (1r,2s,5r)-, N-(4-methoxyphenyl)-5-methyl-2- (1-methylethyl)cyclohexanecarboxamide, (1r,2s,5r)-