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Digoxin Immune Fab (Ovine)
go.drugbank.com/drugs/DB00076ApprovedIt is used as an antidote for overdose of digoxin.
Dinitrochlorobenzene
go.drugbank.com/drugs/DB11831InvestigationalDinitrochlorobenzene has been used in trials studying the treatment of HIV Infections.
Categories: Compounds used in a research, industrial, or household settingEstrone
go.drugbank.com/drugs/DB00655ApprovedIt is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione. … Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol.
Nitrocefin
go.drugbank.com/drugs/DB11592ExperimentalNitrocefin is a chromogenic cephalosporin substrate used to detect the presence of beta-lactamase enzymes, an important mediator of bacterial antibiotic resistance.
Categories: Compounds used in a research, industrial, or household settingNNZ-2591
go.drugbank.com/drugs/DB15601InvestigationalIt was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by the European Patent Office in December 2019. … [L11100] Clinical trials are expected to begin in 2020.[L11103,L11100]
JSM 6427
go.drugbank.com/drugs/DB06139InvestigationalIt has been biologically validated for therapeutic use in the prevention and treatment of wet AMD, the leading cause of blindness in people over the age of 55.
Desirudin
go.drugbank.com/drugs/DB11095ApprovedWithdrawnIt has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. … It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients.
Phosmet
go.drugbank.com/drugs/DB11448ExperimentalVet approvedIt is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals, and vines to control aphids, suckers, mites, and fruit flies.
Categories: Compounds used in a research, industrial, or household settingSPP 301
go.drugbank.com/drugs/DB05290InvestigationalSPP301 (Avosentan) is a potent and highly selective ET[A] receptor blocker and is clinically investigated in diabetic nephropathy.
LC16M8
go.drugbank.com/drugs/DB05019InvestigationalIt is the only attenuated vaccine to be licensed for use in humans to prevent smallpox infection.