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Samarium
go.drugbank.com/drugs/DB12403InvestigationalSamarium has been used in trials studying the treatment and prevention of Pain, Cancer, Metastasis, Prostate Cancer, and Metastatic Osteosarcoma, among others.
9-aminocamptothecin
go.drugbank.com/drugs/DB12515InvestigationalAminocamptothecin has been used in trials studying the treatment of Lymphoma, Gastric Cancer, Ovarian Cancer, Esophageal Cancer, and Ovarian Neoplasms, among others.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesPhenethyl Isothiocyanate
go.drugbank.com/drugs/DB12695InvestigationalPhenethyl Isothiocyanate has been used in trials studying the prevention and treatment of Leukemia, Lung Cancer, Tobacco Use Disorder, and Lymphoproliferative Disorders.
Categories: Compounds used in a research, industrial, or household settingEsomeprazole
go.drugbank.com/drugs/DB00736ApprovedInvestigationalEsomeprazole has been shown to inhibit acid secretion to a similar extent as [DB00338], without any significant differences between the two compounds _in vitro_. … Esomeprazole is the s-isomer of [DB00338], which is a racemate of the S- and R-enantiomer.
Mixtures: RUMONAL® PRO 15, RUMONAL® PRO 7.5Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsKP-1461
go.drugbank.com/drugs/DB05644InvestigationalDesignated a DNA covert nucleoside, the drug consists of a modified base that incorporates randomly into HIV and pairs with multiple bases. … KP-1461 is a potent, non-chain-terminating, mutagenic deoxyribonucleoside analogue.
NLX-P101
go.drugbank.com/drugs/DB05924ExperimentalNLX-P101, gene therapy is developed by Neurologix to treat Parkinson’s disease. … The gene is glutamic acid decarboxylase (GAD), whose product synthesizes the major inhibitory neurotransmitter in the brain, (gamma)-aminobutyric acid (GABA), and targets the subthalamic nucleus (STN),
Vadimezan
go.drugbank.com/drugs/DB06235InvestigationalSynonyms: (5,6-dimethyl-9-oxoxanthen-4-yl)acetic acid, 5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acidCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 3-RingBafetinib
go.drugbank.com/drugs/DB11851InvestigationalBafetinib has been used in trials studying the treatment of Adult Gliosarcoma, Adult Mixed Glioma, Adult Glioblastoma, Chronic Myeloid Leukemia, and Acute Lymphocytic Leukemia, among others.
Categories: Heterocyclic Compounds, 1-RingPlumbagin
go.drugbank.com/drugs/DB17048InvestigationalPlumbagin is a compound investigated for its anticancer activity. It has been found that it inactivates the Akt/NF-kB, MMP-9 and VEGF pathways.[A253102]
Categories: Compounds used in a research, industrial, or household settingSynonyms: 5-hydroxy-2-methyl-1,4-naphthalenedionePresatovir
go.drugbank.com/drugs/DB12165InvestigationalPresatovir has been used in trials studying the treatment of RSV Infection, Respiratory Syncytial Virus (RSV), Respiratory Syncytial Virus Infections, and Respiratory Syncytial Virus (RSV) Infections.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring