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Oprelvekin
go.drugbank.com/drugs/DB00038ApprovedInvestigationalWithdrawnIn animal studies, oprelvekin was also shown to regulate intestinal epithelium growth by enhancing healing of gastrointestinal lesions, inhibit adiopegenesis and macrophageal released pro-inflammatory … In mice and nonhuman primate studies of animals with moderate and severe myelosuppression, in addition to compromised hematopoiesis, oprelvekin was shown to potently induce thrombopoiesis and improve platelet
Eteplirsen
go.drugbank.com/drugs/DB06014ApprovedInvestigationalEteplirsen was the first treatment for DMD approved by the FDA.[A244925] … Eteplirsen was first approved by the FDA in September 2016 for the treatment of Duchenne muscular dystrophy (DMD) in patients with a confirmed mutation of the DMD gene, which codes for dystrophin, that
PRO 2000
go.drugbank.com/drugs/DB05385InvestigationalPRO 2000 is an investigational medicine that is not yet approved by the FDA for use outside of clinical trials. It is being studied for the prevention of HIV infection and other sexually transmitted diseases. This medicine does not cure ...
P54
go.drugbank.com/drugs/DB05451ExperimentalIt inhibits the induction of the enzyme NFkB, thereby inhibiting downstream inflammatory genes such as COX II and iNOS.
Fludeoxyglucose (18F)
go.drugbank.com/drugs/DB09502ApprovedInvestigationalFludeoxyglucose F 18 Injection is a positron emitting radiopharmaceutical containing no-carrier added radioactive 2-deoxy-2-[18F]fluoro-D-g1ucose, which is used for diagnostic purposes in conjunction with Positron Emission Tomography (PE...
CCX915
go.drugbank.com/drugs/DB05159ExperimentalThe CCR2 receptor is thought to be of central importance to inflammatory diseases, such as multiple sclerosis (MS), Type II diabetes and atherosclerosis.
Balsalazide
go.drugbank.com/drugs/DB01014ApprovedMesalazine is also known as 5-aminosalicylic acid, or 5-ASA. … It is usually administered as the disodium salt. Balsalazide works by deliverying mesalazine to the large intestine to act directly on ulcerative colitis.
Primaquine
go.drugbank.com/drugs/DB01087ApprovedInvestigationalIt has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria.
Olomorasib
go.drugbank.com/drugs/DB21697InvestigationalOlomorasib has a monoisotopic molecular weight of 528.08 Da. … The usage of the INN stem '-rasib' in the name indicates that Olomorasib is a Ras protein inhibitor.
Bavituximab
go.drugbank.com/drugs/DB05136InvestigationalBavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections.