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Cinoxacin
go.drugbank.com/drugs/DB00827ApprovedWithdrawnSynthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.
Adenosine 5'-[gamma-thio]triphosphate
go.drugbank.com/drugs/DB02930ExperimentalA nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.
Categories: Compounds used in a research, industrial, or household settingInfluenza A virus A/Washington/19/2020 (H1N1) antigen (MDCK cell derived, propiolactone inactivated)
go.drugbank.com/drugs/DB16727ApprovedWithdrawnInactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Mercuric chloride
go.drugbank.com/drugs/DB13765ExperimentalMercuric chloride was used to disinfect wounds by Arab physicians in the Middle Ages but modern medicine has since deemed it unsafe for use. [T112]
Categories: Compounds used in a research, industrial, or household settingCisapride
go.drugbank.com/drugs/DB00604ApprovedWithdrawnIn many countries (including Canada) cisapride has been either withdrawn or has had its indications limited due to reports about long QT syndrome due to cisapride, which predisposes to arrhythmias.
Desirudin
go.drugbank.com/drugs/DB11095ApprovedWithdrawnIt has a protein structure that is similar to that of hirudin, the naturally occurring anticoagulant present in the peripharyngeal glands in the medicinal leech, Hirudo medicinalis. … It is mainly indicated for the prevention of deep vein thrombosis in hip replacement surgery patients.
Teniposide
go.drugbank.com/drugs/DB00444ApprovedInvestigationalAccumulated breaks in DNA prevent cells from entering into the mitotic phase of the cell cycle, and lead to cell death. Teniposide acts primarily in the G2 and S phases of the cycle. … This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding.
Estrone
go.drugbank.com/drugs/DB00655ApprovedIt is produced primarily in the ovaries, placenta, and in peripheral tissues (especially adipose tissue) through conversion of adrostenedione. … Estrone, one of the major mammalian estrogens, is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone. It is produced in vivo from androstenedione or from testosterone via estradiol.
Taberminogene vadenovec
go.drugbank.com/drugs/DB05011ExperimentalThe initial target market is haemodialysis graft access surgery, a procedure in which patients whose kidneys have failed have a plastic tube grafted between blood vessels generally in their forearm so
SPP 301
go.drugbank.com/drugs/DB05290InvestigationalSPP301 (Avosentan) is a potent and highly selective ET[A] receptor blocker and is clinically investigated in diabetic nephropathy.