This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Mercuric chloride
DrugBank Accession Number
DB13765
Background

Mercury chloride (HgCl2) is a highly toxic compound that volatizes slightly at ordinary temperature and appreciably at 100 degrees C. It is corrosive to mucous membranes and used as a topical antiseptic and disinfectant. Mercuric chloride was used to disinfect wounds by Arab physicians in the Middle Ages but modern medicine has since deemed it unsafe for use. 1

Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 271.5
Monoisotopic: 271.908331018
Chemical Formula
Cl2Hg
Synonyms
  • bichlorure de mercure
  • chlorure mercurique
  • corrosive mercury chloride
  • corrosive sublimate
  • dichloromercury
  • dichlorure de mercure
  • hydrargyrum bichloratum
  • mercuric bichloride
  • Mercuric chloride
  • mercury bichloride
  • mercury perchloride
  • Mercury(II) chloride
  • Quecksilber(II)-chlorid
  • Sublimat
  • sublimate
  • Sulema
External IDs
  • TL 898

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
Build, train, & validate machine-learning models
with evidence-based and structured datasets.
See how
Build, train, & validate predictive machine-learning models with structured datasets.
See how
Contraindications & Blackbox Warnings
Contraindications
Avoid life-threatening adverse drug events
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Learn more
Avoid life-threatening adverse drug events & improve clinical decision support.
Learn more
Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
Improve decision support & research outcomes
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
Learn more
Improve decision support & research outcomes with our structured adverse effects data.
Learn more
Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

ATC Codes
D08AK03 — Mercuric chloride
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as transition metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a transition metal.
Kingdom
Inorganic compounds
Super Class
Mixed metal/non-metal compounds
Class
Transition metal salts
Sub Class
Transition metal chlorides
Direct Parent
Transition metal chlorides
Alternative Parents
Inorganic chloride salts / Inorganic mercury compounds
Substituents
Inorganic chloride salt / Inorganic mercury compound / Inorganic salt / Transition metal chloride
Molecular Framework
Not Available
External Descriptors
mercury coordination entity (CHEBI:31823) / Inorganic fungicides (C13377)
Affected organisms
Not Available

Chemical Identifiers

UNII
53GH7MZT1R
CAS number
7487-94-7
InChI Key
LWJROJCJINYWOX-UHFFFAOYSA-L
InChI
InChI=1S/2ClH.Hg/h2*1H;/q;;+2/p-2
IUPAC Name
dichloromercury
SMILES
Cl[Hg]Cl

References

General References
  1. Maillard, Adam P. Fraise, Peter A. Lambert, Jean-Yves (2007). Principles and Practice of Disinfection, Preservation and Sterilization (pp. 4). Oxford: John Wiley & Sons. [ISBN:0470755067]
KEGG Drug
D01905
KEGG Compound
C13377
ChemSpider
22517
RxNav
1311634
ChEBI
31823
ChEMBL
CHEMBL1374360
Wikipedia
Mercury(II)_chloride

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.57ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity12.27 m3·mol-1ChemAxon
Polarizability7.27 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created at June 23, 2017 20:48 / Updated at February 21, 2021 18:54