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Displaying results 3821 - 3830 of 10000 in total
  1. Drug

    Trestolone

    go.drugbank.com/drugs/DB05830
    Investigational

    Trestolone (7α-methyl-19-nortestosterone) is a synthetic androgen developed by the Population Council as a potential candidate drug for use in hormonal male contraceptive methods. … In males, regular administration of sufficient quantities of trestolone induces a state of temporary infertility.

    Synonyms: 17beta-Hydroxy-7alpha-methylestr-4-en-3-one
  2. Drug

    Albendazole

    go.drugbank.com/drugs/DB00518
    ApprovedInvestigationalVet approved

    A benzimidazole broad-spectrum anthelmintic structurally related to mebendazole that is effective against many diseases. (From Martindale, The Extra Pharmacopoeia, 30th ed, p38)

    Synonyms: O-methyl N-(5-(propylthio)-2-benzimidazolyl)carbamate
  3. Drug

    Telithromycin

    go.drugbank.com/drugs/DB00976
    Approved

    It is used to treat mild to moderate respiratory infections. … Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one.

  4. Drug

    Thiothixene

    go.drugbank.com/drugs/DB01623
    Approved

    A thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.

  5. Drug

    Norfloxacin

    go.drugbank.com/drugs/DB01059
    ApprovedInvestigational

    A synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.

    Categories: Topoisomerase II InhibitorsProducts: N-FLOXA 200, N-FLOXA 400
  6. Drug

    Dithioerythritol

    go.drugbank.com/drugs/DB01692
    Experimental

    A compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl

    Categories: Compounds used in a research, industrial, or household setting
  7. Drug

    ILY101

    go.drugbank.com/drugs/DB05059
    Investigational

    ILY101 is designed to allow for lower daily doses and improved patient acceptance and tolerability in comparison to other products in this class of drugs. … ILY101 is being developed for the treatment of hyperphosphatemia in CKD patients on dialysis and works by reducing the systemic absorption of dietary phosphate.

  8. Drug

    Taberminogene vadenovec

    go.drugbank.com/drugs/DB05011
    Experimental

    The initial target market is haemodialysis graft access surgery, a procedure in which patients whose kidneys have failed have a plastic tube grafted between blood vessels generally in their forearm so … EG004 has completed a Phase II trial, this being the first part of the Phase II/III study for which it has received approval from the US Recombinant DNA Advisory Committee (RAC).

  9. Drug

    Rivanicline

    go.drugbank.com/drugs/DB05855
    Experimental

    It has subsequently been developed as a potential anti-inflammatory treatment for ulcerative colitis. … Rivanicline (TC-2403, RJR-2403, (E)-metanicotine) is a partial agonist at neuronal nicotinic acetylcholine receptors, binding primarily to the α4β2 subtype.

    Synonyms: (3E)-N-methyl-4-(pyridin-3-yl)but-3-en-1-amine, (E)-N-Methyl-4-(3-pyridinyl)-3-butene-1-amine
  10. Drug

    MBO7133

    go.drugbank.com/drugs/DB04999
    Experimental

    However, araC is only slowly converted to araCTP in the liver or in primary liver tumors due to low levels of an enzyme in the liver that is required for the conversion of araC to araCMP, the first step … in the activation pathway of the drug.