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Amdinocillin
go.drugbank.com/drugs/DB01163ApprovedInvestigationalWithdrawnIt is poorly absorbed if given orally and is used in urinary infections and typhus. Amdinocillin is not available in the United States.
Synonyms: Penicillin HXCategories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseAminopterin
go.drugbank.com/drugs/DB08878ApprovedWithdrawnIn the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment of psoriasis. … Aminopterin is an amino derivative of folic acid, which was once used as an antineoplastic agent in the treatment of pediatric leukemia.
Synonyms: N-(4-(((2,4-diamino-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acidTarenflurbil
go.drugbank.com/drugs/DB05289InvestigationalIt is a selective amyloid lowering agent (SALA) that reduces levels of the toxic peptide amyloid beta 42 (Aβ42) in cultured human cells and in animal models. … In June 2008 development of the drug for Alzheimer's disease was discontinued. Tarenflurbil has also been used in trials studying the treatment of Prostate Cancer.
Synonyms: (R)-flurbiprofen, (R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acidCategories: Analgesics, Non-NarcoticBrivudine
go.drugbank.com/drugs/DB03312ApprovedInvestigationalBrivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseTolazoline
go.drugbank.com/drugs/DB00797ApprovedVet approvedWithdrawnIt is used in treatment of persistent pulmonary hypertension of the newborn. … A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output.
Categories: Topical Products for Joint and Muscular PainEtamivan
go.drugbank.com/drugs/DB08989ApprovedWithdrawnEtamivan (INN) or ethamivan (USAN) is marketed under the name Analepticon. Etamvin is a respiratory stimulant drug similar to nikethamide. It is no longer used in the United States.
Octyl triazone
go.drugbank.com/drugs/DB15469InvestigationalMixtures: PURITO Centella Green Level Safe Sun, Kiehls Activated Sun Protector Sunscreen SPF 50 For Face and Body For All Skin TypesDigitoxin
go.drugbank.com/drugs/DB01396ApprovedWithdrawnA cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting.
Categories: Compounds used in a research, industrial, or household settingChlorotoxin I-131
go.drugbank.com/drugs/DB05462InvestigationalChlorotoxin I-131 is investigated in clinical trials for treating brain cancer. … The synthetic version of this peptide has been manufactured and covalently linked to iodine 131 as a means of targeting radiation to tumor cells in the treatment of brain cancer.
Synonyms: I(131)-TM-601 (chlorotoxin)EHT899
go.drugbank.com/drugs/DB05108ExperimentalIt also apparently enhances a secondary immune response to clear the viral infection, resulting in reduction in liver damage and decrease in viral load. … EHT899 is a proprietary formulation of an HBV viral protein designed to eliminate the undesirable immune response elicited by the HBV infection.